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. 2025 Oct;56(5):1214-1224.
doi: 10.1007/s10578-023-01653-3. Epub 2024 Feb 10.

Characterizing Measurement-Based Care in the Texas Youth Depression and Suicide Research Network (TX-YDSRN)

Holli Slater  1 , Yasmin AlZubi  1 , Afsaneh Rezaeizadeh  1 , Jennifer L Hughes  2 , April Gorman  1 , Taryn L Mayes  1 , Joshua S Elmore  1 , Eric A Storch  3 , Sarah M Wakefield  4 , Madhukar H Trivedi  5
Affiliations

Characterizing Measurement-Based Care in the Texas Youth Depression and Suicide Research Network (TX-YDSRN)

Holli Slater et al. Child Psychiatry Hum Dev. 2025 Oct.

Abstract

Integration of measurement-based care (MBC) into clinical practice has shown promise in improving treatment outcomes for depression. Yet, without a gold standard measure of MBC, assessing fidelity to the MBC model across various clinical settings is difficult. A central goal of the Texas Youth Depression and Suicide Research Network (TX-YDSRN) was to characterize MBC across the state of Texas through the development of a standardized tool to assess the use of MBC strategies when assessing depression, anxiety, side effects, and treatment adherence. A chart review of clinical visits indicated standardized depression measures (71.2%) and anxiety measures (64%) were being utilized across sites. The use of standardized measures to assess medication adherence and side effects was limited to less than six percent for both, with the majority utilizing clinical interviews to assess adherence and side effects; yet medication was changed in nearly half. Rates of utilization of standardized measures for participants with multiple MBC forms were similar to those who only provided one form.

Keywords: Adolescents; Assessment; Children; Depression; Measurement-based care.

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Conflict of interest statement

Declarations. Conflict of interest: Dr. Hughes reports receiving research funding to her institution from NIH. She reports receiving support from the Society of Clinical Child and Adolescent Psychology, the Jed Foundation, and Mental Health in Mind, International AB, and consulting on quality improvement interventions for depression and suicidal/self-harm behavior. She receives book royalties from Guilford Press. Dr. Storch reports receiving research funding to his institution from the Ream Foundation, International OCD Foundation, and NIH. He is a consultant for Brainsway and Biohaven Pharmaceuticals. He owns stock less than $5000 in NView. He receives book royalties from Elsevier, Wiley, Oxford, American Psychological Association, Guildford, Springer, Routledge, and Jessica Kingsley. Dr. Trivedi has provided consulting services to Alkermes Inc, Axsome Therapeutics, Biogen MA Inc., Cerebral Inc., Circular Genomics Inc, Compass Pathfinder Limited, GH Research Limited, Heading Health Inc, Janssen, Legion Health Inc, Merck Sharp & Dohme Corp., Mind Medicine (MindMed) Inc, Merck Sharp & Dhome LLC, Naki Health, Ltd., Neurocrine Biosciences Inc, Noema Pharma AG, Orexo US Inc, Otsuka American Pharmaceutical Inc, Otsuka Canada Pharmaceutical Inc, Otsuka Pharmaceutical Development & Commercialization Inc, Praxis Precision Medicines Inc, SAGE Therapeutics, Sparian Biosciences Inc, Takeda Pharmaceutical Company Ltd, WebMD. He sits on the Scientific Advisory Board of Alto Neuroscience Inc, Cerebral Inc., Compass Pathfinder Limited, Heading Health, GreenLight VitalSign6 Inc, Legion Health Inc, Merck Sharp & Dohme Corp, Orexo US Inc, Signant Health. He holds stock in Alto Neuroscience Inc, Cerebral Inc, Circular Genomics Inc, GreenLight VitalSign6 Inc, Legion Health Inc. Additionally, he has received editorial compensation from American Psychiatric Association, and Oxford University Press. Dr. Slater, Ms. AlZubi, Ms. Rezaeizadeh, Ms. Gorman, Ms. Mayes, Mr. Elmore, and Dr. Wakefield have no declarations to report. Ethical approval: The UT Southwestern IRB served as a single IRB of record for all Nodes; Node IRBs also reviewed the study. For participants under 18 years of age, a parent or guardian provides written informed consent, and the adolescent provides written informed assent. For participants ages 18 years and older, the participant provides written informed consent. Data presented within this manuscript are related to node-subsites; participant level data is not presented.

Figures

Fig. 1
Fig. 1
A Appearance of the clinical dashboard summary. B Longitudinal patient research data reported to the node subsite clinicians
See this image and copyright information in PMC

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