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. 2024 Feb 9;7(2):e1855.
doi: 10.1002/hsr2.1855. eCollection 2024 Feb.

Inversion of CD4:CD8 ratio in 50 cutaneous biopsies of patients with Kaposi sarcoma and human immunodeficiency virus infection: A cross-sectional, descriptive, and observational study in a single dermatology center

Alejandro García-Irigoyen  1 , Simón Guzmán-Bucio  1 , Mercedes Aranda-Audelo  2 , Zonía R Moore  3 , Héctor Trinidad-Bibiano  4 , Vega-Memije María Elisa  1
Affiliations

Inversion of CD4:CD8 ratio in 50 cutaneous biopsies of patients with Kaposi sarcoma and human immunodeficiency virus infection: A cross-sectional, descriptive, and observational study in a single dermatology center

Alejandro García-Irigoyen et al. Health Sci Rep. .
No abstract available

Keywords: CD4:CD8 ratio; HIV; Kaposi sarcoma; exhausted lymphocytes.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Immunochemistry of Kaposi sarcoma (KS). CD8+ TL cells are illustrated in brown color and CD4+ TL cells in red color. Plaque stage (A) and tumoral stage (B) of KS in a ×20 field. Patch stage of KS in a ×60 field (C). Plaque stage of KS in a ×60 field (D). Tumoral stage of KS in a ×60 field (E). A perivascular CD8+ TL predominance in the endothelial proliferation of KS are observed, however, a lower CD8+ TL count was presented in tumoral stages compared with patch and plaque stages.
Figure 2
Figure 2
Box plot of histological stadium in Kaposi sarcoma and cutaneous CD8+ T‐cells counts.
See this image and copyright information in PMC

References

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