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. 2024 Apr;26(4):660-668.
doi: 10.1111/codi.16895. Epub 2024 Feb 12.

SF-CORNER (splenic flexure colorectal cancer): an international survey of operative approaches and outcomes for cancers of the splenic flexure

H Sekhar  1 , M Dyer  2 , M Khan  3 , P J Mitchell  4 , N P West  5 , S Moug  6 , D Vimalachandran  7 ; SF‐CORNER collaborative study group
Collaborators, Affiliations

SF-CORNER (splenic flexure colorectal cancer): an international survey of operative approaches and outcomes for cancers of the splenic flexure

H Sekhar et al. Colorectal Dis. 2024 Apr.

Abstract

Aim: The optimum surgical approach to splenic flexure cancers (SFCs) remains uncertain. The aim of this survey was to explore the opinions of an international surgical community on the management and outcomes of SFC.

Method: A questionnaire was constructed comprising five sections (information about respondents; definition and prognosis of SFC; operative approach; approach in specific scenarios; outcomes) and circulated through an international dissemination committee and social media.

Results: The survey received 576 responses over 4 weeks across 50 countries. There was no consensus regarding the definition of the splenic flexure, whilst the proportion of respondents who did and did not think that patients with SFC had a worse outcome was equal. The overall preferred operative approach was left hemicolectomy [203 (35.2%)], followed by segmental resection [167 (29%)], extended right hemicolectomy [126 (21.9%)] and subtotal colectomy [7 (12%)]. The stated pedicles for ligation varied between resection types and also within the same resection. One hundred and sixty-six (28.8%) respondents thought a segmental resection was associated with the worst survival and 190 (33%) thought it was associated with the best quality of life.

Conclusion: This survey confirms a lack of consensus across all aspects SFC treatment. The differing approaches described are likely to represent different beliefs around the variable anatomy of this region and the associated lymphatic drainage. Future studies are required to address such inconsistencies and identify the optimum surgical strategy, whilst also incorporating quality-of-life metrics and patient-reported outcomes. A one-size-fits-all approach is probably not appropriate with SFC, and a more bespoke approach is required.

Keywords: colonic resection; nodal mapping; personalised treatment; splenic flexure cancers.

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Conflict of interest statement

All authors have no conflicts of interest to declare.

Figures

FIGURE 1
FIGURE 1
An alluvial diagram demonstrating proportional correlations between colonic resections respondents stated as their preferred approach to splenic flexure cancer (on the left) and the pedicles they describe dividing as part of that resection (on the right): ICA, ileocolic artery; IMA, inferior mesenteric artery; LCA, left colic artery; LMCA, left branch of the middle colic artery; MCA, middle colic artery; RMCA, right branch of the middle colic artery.
FIGURE 2
FIGURE 2
(A) Bar chart demonstrating which resection type respondents thought were associated with the best and worst survival. (B) Bar chart demonstrating which resection type respondents thought were associated with the best and worst quality of life (QoL).
See this image and copyright information in PMC

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