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Meta-Analysis
. 2024 Feb;10(1):e839.
doi: 10.1002/cre2.839.

Effectiveness of mechanical and chemical decontamination methods for the treatment of dental implant surfaces affected by peri-implantitis: A systematic review and meta-analysis

Iain Hart  1 , Christine Wells  2 , Alexandra Tsigarida  1 , Beatriz Bezerra  3
Affiliations
Meta-Analysis

Effectiveness of mechanical and chemical decontamination methods for the treatment of dental implant surfaces affected by peri-implantitis: A systematic review and meta-analysis

Iain Hart et al. Clin Exp Dent Res. 2024 Feb.

Abstract

Objective: To assess which decontamination method(s) used for the debridement of titanium surfaces (disks and dental implants) contaminated with bacterial, most efficiently eliminate bacterial biofilms.

Material and methods: A systematic search was conducted in four electronic databases between January 1, 2010 and October 31, 2022. The search strategy followed the PICOS format and included only in vitro studies completed on either dental implant or titanium disk samples. The assessed outcome variable consisted of the most effective method(s)-chemical or mechanical- removing bacterial biofilm from titanium surfaces. A meta-analysis was conducted, and data was summarized through single- and multi-level random effects model (p < .05).

Results: The initial search resulted in 5260 articles after the removal of duplicates. After assessment by title, abstract, and full-text review, a total of 13 articles met the inclusion criteria for this review. Different decontamination methods were assessed, including both mechanical and chemical, with the most common method across studies being chlorhexidine (CHX). Significant heterogeneity was noted across the included studies. The meta-analyses only identified a significant difference in biofilm reduction when CHX treatment was compared against PBS. The remaining comparisons did not identify significant differences between the various decontamination methods.

Conclusions: The present results do not demonstrate that one method of decontamination is superior in eliminating bacterial biofilm from titanium disk and implant surfaces.

Keywords: biofilm; decontamination; dental implants; periimplantitis.

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Conflict of interest statement

The authors declare no conflict of interest.

Figures

Figure 1
Figure 1
Flowchart of search and selection process.
Figure 2
Figure 2
Meta‐analysis for the comparison between PBS and H2O2 decontamination methods.
Figure 3
Figure 3
Meta‐analysis for the comparison between PBS and photosensitizing agent decontamination methods.
Figure 4
Figure 4
Meta‐analysis for the comparison between PBS and LASER decontamination methods.
Figure 5
Figure 5
Meta‐analysis for the comparison between chlorhexidine and H2O2 decontamination methods.
See this image and copyright information in PMC

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