Morphofunctional State of the Ovaries in Rats with Experimental Model of Functional Cysts and Their Treatment with Gonadotropin-Releasing Hormone Antagonist
- PMID: 38345676
- DOI: 10.1007/s10517-024-06034-x
Morphofunctional State of the Ovaries in Rats with Experimental Model of Functional Cysts and Their Treatment with Gonadotropin-Releasing Hormone Antagonist
Abstract
The morphofunctional features of the ovaries were evaluated in rats with functional ovarian cysts model treated with gonadotropin-releasing hormone antagonist. Administration of the antagonist significantly (p=0.009) reduced the number of cysts and the growth of follicles in the ovaries. The obtained results attest to a possibility of successful treatment of functional ovarian cysts with gonadotropin-releasing hormone antagonist.
Keywords: functional ovarian cysts; functional ovarian cysts treatment; gonadotropin-releasing hormone antagonist; ovarian morphology.
© 2024. Springer Science+Business Media, LLC, part of Springer Nature.
References
-
- Gasymova DM, Rukhlyada NN. Clinical and anamnestic characteristics of patients with complications of benign tumors and tumor-like masses of the ovary. Ross. Vestn. Akush. Gin. 2017;17(4):72-77. Russian. doi: https://doi.org/10.17116/rosakush201717472-77
-
- Reissmann T, Schally AV, Bouchard P, Riethmiiller H, Engel J. The LHRH antagonist cetrorelix: a review. Hum. Reprod. Update. 2000;6(4):322-331. doi: https://doi.org/10.1093/humupd/6.4.322 - DOI - PubMed
-
- Logvinov SV, Tikhonovskaja OA, Petrova MS, Bukharina IJ, Petrov IA, Petrina JV, Okorokov AO, Alitkina ES. Patent RU No. 2282249. Method for modeling polycystic ovaries at predominance of follicular cysts. Bull. No. 23. Published August 20, 2006.
-
- Baak JPA, Oort J. A Manual of Morphometry in Diagnostic Pathology. Springer Science & Business Media, 2012.
-
- Woldemeskel M. Toxicologic pathology of the reproductive system. Reproductive and Developmental Toxicology (second edition). Gupta RC, ed. San Diego, 2017. P. 1209-1241. doi: https://doi.org/10.1016/B978-0-12-804239-7.00064-0
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