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Editorial
. 2023 Dec;18(4):672-678.
doi: 10.26574/maedica.2023.18.4.672.

Platelet-Rich Fibrin in Otorhinolaryngology

Konstantina Dinaki  1 , Nikolaos Grigoriadis  2 , Constantinos Papadopoulos  3 , Ioannis Vizirianakis  4   5 , Jannis Constantinidis  6 , Stefanos Triaridis  6 , Petros Karkos  6
Affiliations
Editorial

Platelet-Rich Fibrin in Otorhinolaryngology

Konstantina Dinaki et al. Maedica (Bucur). 2023 Dec.

Abstract

Background: Platelet-rich fibrin is a second-generation platelet concentrate. It is rich in platelets, cytokines, growth factors and leukocytes. Compared to platelet-rich plasma, it releases growth factors for a more extended amount of time. Methods:A literature review was conducted on the applications of platelet-rich fibrin in otolaryngology. Only articles written in English were further considered for the study; all others were excluded. Also, articles relating to oral and maxillofacial surgery were removed. Results: Twenty-five studies were deemed appropriate for inclusion in the present review. Conclusion:Based on the current data, platelet-rich fibrin appears to be a safe, healing-promoting material. It is a cost-effective, autologous material with enormous therapeutic application potential in the future. However, further clinical research is required before conclusive conclusions can be drawn about its usefulness.

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Figures

FIGURE 1.
FIGURE 1.
Platelet-rich fibrin preparation by centrifugation of blood sample collected without anticoagulant
TABLE 1.
TABLE 1.
PRF in laryngology surgery
TABLE 2.
TABLE 2.
PRF in rhinology and skull base surgery
TABLE 3.
TABLE 3.
PRF in otology surgery
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