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Comment
. 2024 Jul 1;80(1):11-13.
doi: 10.1097/HEP.0000000000000771. Epub 2024 Feb 13.

enHanCCing knowledge of genetic factors in primary liver tumor

Jill Koshiol  1 , Marcin Krawczyk  2   3
Affiliations
Comment

enHanCCing knowledge of genetic factors in primary liver tumor

Jill Koshiol et al. Hepatology. .
No abstract available

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Conflict of interest statement

Conflict of interest: NONE.

Figures

Figure 1.
Figure 1.
Overview of genetic variants linked to the increased risk of hepatocellular carcinoma (HCC) in patients with non-viral (left side) and viral (right side) liver diseases, as reported by Manal et al. The x-axis presents the genes that have been found to be associated with HCC risk. The boxes above each gene present the odds ratio (OR) with the middle line, and the associated confidence intervals with the upper and lower lines, indicating the likelihood of developing HCC among patients with each specific variant.
See this image and copyright information in PMC

Comment on

  • Genetic variation in TERT modifies the risk of hepatocellular carcinoma in alcohol-related cirrhosis: results from a genome-wide case-control study.
    Buch S, Innes H, Lutz PL, Nischalke HD, Marquardt JU, Fischer J, Weiss KH, Rosendahl J, Marot A, Krawczyk M, Casper M, Lammert F, Eyer F, Vogel A, Marhenke S, von Felden J, Sharma R, Atkinson SR, McQuillin A, Nattermann J, Schafmayer C, Franke A, Strassburg C, Rietschel M, Altmann H, Sulk S, Thangapandi VR, Brosch M, Lackner C, Stauber RE, Canbay A, Link A, Reiberger T, Mandorfer M, Semmler G, Scheiner B, Datz C, Romeo S, Ginanni Corradini S, Irving WL, Morling JR, Guha IN, Barnes E, Ansari MA, Quistrebert J, Valenti L, Müller SA, Morgan MY, Dufour JF, Trebicka J, Berg T, Deltenre P, Mueller S, Hampe J, Stickel F. Buch S, et al. Gut. 2023 Feb;72(2):381-391. doi: 10.1136/gutjnl-2022-327196. Epub 2022 Jul 4. Gut. 2023. PMID: 35788059 Free PMC article.

References

    1. Llovet JM, Kelley RK, Villanueva A, et al. Hepatocellular carcinoma. Nat Rev Dis Primers. Jan 21 2021;7(1):6. doi: 10.1038/s41572-020-00240-3 - DOI - PubMed
    1. Singal AG, Llovet JM, Yarchoan M, et al. AASLD Practice Guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma. Hepatology. Dec 1 2023;78(6):1922–1965. doi: 10.1097/HEP.0000000000000466 - DOI - PMC - PubMed
    1. El-Serag HB, Rudolph KL. Hepatocellular carcinoma: epidemiology and molecular carcinogenesis. Gastroenterology. Jun 2007;132(7):2557–76. doi: 10.1053/j.gastro.2007.04.061 - DOI - PubMed
    1. Wangensteen KJ, Chang KM. Multiple Roles for Hepatitis B and C Viruses and the Host in the Development of Hepatocellular Carcinoma. Hepatology. Jan 2021;73 Suppl 1(Suppl 1):27–37. doi: 10.1002/hep.31481 - DOI - PMC - PubMed
    1. Visscher PM, Wray NR, Zhang Q, et al. 10 Years of GWAS Discovery: Biology, Function, and Translation. Am J Hum Genet. Jul 6 2017;101(1):5–22. doi: 10.1016/j.ajhg.2017.06.005 - DOI - PMC - PubMed

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