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. 2024 Feb 13:13:e54707.
doi: 10.2196/54707.

Supporting Life Adjustment in Patients With Lung Cancer Through a Comprehensive Care Program: Protocol for a Controlled Before-and-After Trial

Wonyoung Jung #  1   2 , Alice Ahn #  3   4 , Genehee Lee  3 , Sunga Kong  3   5 , Danbee Kang  3   5   6 , Dongok Lee  3 , Tae Eun Kim  3 , Young Mog Shim  7 , Hong Kwan Kim  7 , Jongho Cho  7 , Juhee Cho #  3   5 , Dong Wook Shin  1   5
Affiliations

Supporting Life Adjustment in Patients With Lung Cancer Through a Comprehensive Care Program: Protocol for a Controlled Before-and-After Trial

Wonyoung Jung et al. JMIR Res Protoc. .

Abstract

Background: Lung cancer diagnosis affects an individual's quality of life as well as physical and emotional functioning. Information on survivorship care tends to be introduced at the end of treatment, but early intervention may affect posttreatment adjustment. However, to the best of our knowledge, no study has explored the effect of early information intervention on the return to work, family, and societal roles of lung cancer survivors.

Objective: We report the study protocol of a comprehensive care prehabilitation intervention designed to facilitate lung cancer survivors' psychological adjustment after treatment.

Methods: A comprehensive care program was developed based on a literature review and a qualitative study of patients with lung cancer and health professionals. The Lung Cancer Comprehensive Care Program consists of educational videos and follow-up visits by a family medicine physician. To prevent contamination, the control group received routine education, whereas the intervention group received routine care and intervention. Both groups completed questionnaires before surgery (T0) and at 1-month (T1), 6-month (T2), and 1-year (T3) follow-up visits after surgery. The primary outcome was survivors' psychological adjustment to cancer 6 months after pulmonary resection.

Results: The historical control group (n=441) was recruited from September 8, 2021, to April 20, 2022, and the intervention group (n=350) was recruited from April 22, 2022, to October 17, 2022. All statistical analyses will be performed upon completion of the study.

Conclusions: This study examined the effectiveness of an intervention that provided general and tailored informational support to lung cancer survivors, ranging from before to the end of treatment.

Trial registration: ClinicalTrials.gov NCT05078918; https://clinicaltrials.gov/ct2/show/NCT05078918.

International registered report identifier (irrid): DERR1-10.2196/54707.

Keywords: adjustment to cancer; cancer; comprehensive care; early intervention; education; educational; lung; lung cancer; lungs; oncology; prehabilitation; pulmonary; respiratory; return to work; survivor; survivors; survivorship; unmet needs.

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Conflict of interest statement

Conflicts of Interest: None declared.

Figures

Figure 1
Figure 1
Flowchart of the Lung Cancer Comprehensive Care Program.
Figure 2
Figure 2
Schedule of enrollment, intervention, allocation, and assessments. CaSUN-Info: Cancer Survivors’ Unmet Needs Measure—Information domain; CAT: Chronic Obstructive Pulmonary Disease Assessment Test; EORTC QLQ C30: European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire—Core 30; EORTC QLQ LC13: European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire—Lung Cancer 13; HADS: Hospital Anxiety and Depression Scale; IPAQ-7: International Physical Activity Questionnaire-Short Form; Mini-MAC: Mini-Mental Adjustment to Cancer; mMRC: Modified Medical Research Council; T0 is baseline (before surgery); T1 is 1 month after surgery; T2 is 6 months after surgery; T3 is 1 year after surgery. *Primary outcome.
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References

    1. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2021;71(3):209–249. doi: 10.3322/caac.21660. https://onlinelibrary.wiley.com/doi/10.3322/caac.21660 - DOI - DOI - PubMed
    1. Jung KW, Won YJ, Hong S, Kong HJ, Im JS, Seo HG. Prediction of cancer incidence and mortality in Korea, 2021. Cancer Res Treat. 2021;53(2):316–322. doi: 10.4143/crt.2021.290. https://europepmc.org/abstract/MED/33735558 crt.2021.290 - DOI - PMC - PubMed
    1. Shin DW, Cho JH, Yoo JE, Cho J, Yoon DW, Lee G, Shin S, Kim HK, Choi YS, Kim J, Zo JI, Shim YM. Conditional survival of surgically treated patients with lung cancer: a comprehensive analyses of overall, recurrence-free, and relative survival. Cancer Res Treat. 2021;53(4):1057–1071. doi: 10.4143/crt.2020.1308. https://europepmc.org/abstract/MED/33705624 crt.2020.1308 - DOI - PMC - PubMed
    1. Yang P, Cheville AL, Wampfler JA, Garces YI, Jatoi A, Clark MM, Cassivi SD, Midthun DE, Marks RS, Aubry MC, Okuno SH, Williams BA, Nichols FC, Trastek VF, Sugimura H, Sarna L, Allen MS, Deschamps C, Sloan JA. Quality of life and symptom burden among long-term lung cancer survivors. J Thorac Oncol. 2012;7(1):64–70. doi: 10.1097/JTO.0b013e3182397b3e. https://linkinghub.elsevier.com/retrieve/pii/S1556-0864(15)31760-3 S1556-0864(15)31760-3 - DOI - PMC - PubMed
    1. Yun YH, Kim YA, Min YH, Chang YJ, Lee J, Kim MS, Lee H, Kim J, Choi YS, Shim YM, Zo JI. Health-related quality of life in disease-free survivors of surgically treated lung cancer compared with the general population. Ann Surg. 2012;255(5):1000–1007. doi: 10.1097/SLA.0b013e31824f1e9e. - DOI - PubMed

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