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Review

Deprescribing To Reduce Medication Harms in Older Adults: Rapid Response

Amy M. Linsky, Aneesa Motala, Emily Lawson, Paul Shekelle
In: Making Healthcare Safer IV: A Continuous Updating of Patient Safety Harms and Practices [Internet]. Rockville (MD): Agency for Healthcare Research and Quality (US); 2023 Jul.
2024 Feb.
Free Books & Documents
Review

Deprescribing To Reduce Medication Harms in Older Adults: Rapid Response

Amy M. Linsky et al.
Free Books & Documents

Excerpt

The overall purpose of this rapid response is to summarize the most relevant and recent literature on deprescribing interventions to reduce polypharmacy or PIMs among adults aged 65 years and over within the United States. The response is organized around the review questions listed below.

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References

    1. Agency for Healthcare Research and Quality. Making Healthcare Safer IV. Rocville, MD; October 2023. https://www.ahrq.gov/research/fiiidings/making-healthcaresafer/mhs4/inde.... Accessed on October 11, 2023.
    1. Takhar S, Nelson N. Deprescribing as a Patient Safety Strategy. 2021. https://psnet.ahrq.gov/primer/deprescribing-patient-safetystrategy#:~:te.... Accessed on October 11, 2023.
    1. Masnoon N, Shakib S, Kalisch-Ellett L, et al. What is polypharmacy? A systematic review of definitions. BMC Geriatr. 2017. Oct 10;17(1):230. doi: 10.1186/s12877-017-0621-2. PMID: 29017448. - DOI - PMC - PubMed
    1. Delara M, Murray L, Jafari B, et al. Prevalence and factors associated with polypharmacy: a systematic review and Meta-analysis. BMC Geriatr. 2022. Jul 19;22(1):601. doi: 10.1186/s12877-022-03279-x. PMID: 35854209. - DOI - PMC - PubMed
    1. Alhawassi TM, Alatawi W, Alwhaibi M. Prevalence of potentially inappropriate medications use among older adults and risk factors using the 2015 American Geriatrics Society Beers criteria. BMC Geriatrics. 2019 2019/May/29; 19(1): 154. doi: 10.1186/s12877-019-1168-1. - DOI - PMC - PubMed

Background/Introductory Information

    1. O'Mahony D. STOPP/START criteria for potentially inappropriate medications/potential prescribing omissions in older people: origin and progress. Expert Rev Clin Pharmacol. 2020. Jan;13(1):15–22. doi: 10.1080/17512433.2020.1697676. PMID: 31790317. Background - DOI - PubMed
    1. Reeve E, To J, Hendrix I, et al. Patient barriers to and enablers of deprescribing: a systematic review. Drugs Aging. 2013. Oct;30(10):793–807. doi: 10.1007/s40266-013-0106-8. PMID: 23912674. Background - DOI - PubMed
    1. Reeve J, Maden M, Hill R, et al. Deprescribing medicines in older people living with multimorbidity and polypharmacy: the TAILOR evidence synthesis. Health Technol Assess. 2022. Jul;26(32):1–148. doi: 10.3310/aafo2475. PMID: 35894932. Background - DOI - PMC - PubMed
    1. Saeed D, Carter G, Parsons C. Interventions to improve medicines optimisation in frail older patients in secondary and acute care settings: a systematic review of randomised controlled trials and non-randomised studies. Int J Clin Pharm. 2022. Feb;44(1):15–26. doi: 10.1007/s11096-021-01354-8. PMID: 34800255. Background - DOI - PMC - PubMed
    1. Santos NS D, Marengo LL, Moraes FD S, et al. Interventions to reduce the prescription of inappropriate medicines in older patients. Rev Saude Publica. 2019. Jan 31;53:7. doi: 10.11606/s1518-8787.2019053000781. PMID: 30726488. Background - DOI - PMC - PubMed

Toolkits

    1. Eastern AHSN. Opioid deprescribing toolkit. n.d. https://easternahsn.org/about-us/ourprojects/opioid-deprescribing-toolkit/. Accessed on September 22, 2023.
    1. GeriatricsCareOnline.org. AGS Deprescribing Toolkit. n.d. https://geriatricscareonline.org/toc/ags-deprescribing-toolkit/TK013. Accessed on September 22, 2023.
    1. National Hospice and Palliative Care Organization. Hospice Medication Deprescribing Toolkit. November 2020. https://www.nhpco.org/wpcontent/uploads/NHPCO_Deprescribing_Toolkit.pdf.

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