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Meta-Analysis
. 2024 Feb 14;19(1):91.
doi: 10.1186/s13019-024-02505-4.

Factors associated with safe and successful postoperative day 1 discharge after lung operations: a systematic review and meta-analysis

Russell Seth Martins  1 , Asad Saulat Fatimi  2 , Amna Irfan Ansari  2 , Hamna Raheel  3 , Kostantinos Poulikidis  1 , M Jawad Latif  1 , Syed Shahzad Razi  1 , Faiz Y Bhora  4
Affiliations
Meta-Analysis

Factors associated with safe and successful postoperative day 1 discharge after lung operations: a systematic review and meta-analysis

Russell Seth Martins et al. J Cardiothorac Surg. .

Abstract

Background: A shorter length of stay (LOS) is associated with fewer hospital-acquired adverse conditions and decreased utilization of hospital resources. While modern perioperative care protocols have enabled some ambitious surgical teams to achieve discharge as early as within postoperative day 1 (POD1), most other teams remain cautious about such an approach due to the perceived risk of missing postoperative complications and increased readmission rates. We aimed to identify factors that would help guide surgical teams aiming for safe and successful POD1 discharge after lung resection.

Methods: We searched the PubMed, Embase, Scopus, Web of Science and CENTRAL databases for articles comparing perioperative characteristics in patients discharged within POD1 (DWPOD1) and after POD1 (DAPOD1) following lung resection. Meta-analysis was performed using a random-effects model.

Results: We included eight retrospective cohort studies with a total of 216,887 patients, of which 22,250 (10.3%) patients were DWPOD1. Our meta-analysis showed that younger patients, those without cardiovascular and respiratory comorbidities, and those with better preoperative pulmonary function are more likely to qualify for DWPOD1. Certain operative factors, such as a minimally invasive approach, shorter operations, and sublobar resections, also favor DWPOD1. DWPOD1 appears to be safe, with comparable 30-day mortality and readmission rates, and significantly less postoperative morbidity than DAPOD1.

Conclusions: In select patients with a favorable preoperative profile, DWPOD1 after lung resection can be achieved successfully and without increased risk of adverse outcomes such as postoperative morbidity, mortality, or readmissions.

Keywords: Early discharge; Lung operation; Postoperative complications; Segmentectomy; Wedge resection.

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Conflict of interest statement

None.

Figures

Fig. 1
Fig. 1
PRISMA Flowchart
Fig. 2
Fig. 2
Meta-Analyses of Cardiovascular Comorbidities. M–H, Mantel–Haenszel; CI, confidence interval; df, degrees of freedom; P, probability value
Fig. 3
Fig. 3
Meta-Analyses of Respiratory Comorbidities. M–H, Mantel–Haenszel; SD, standard deviation; IV, inverse variance; CI, confidence interval; df, degrees of freedom; P, probability value
Fig. 4
Fig. 4
Meta-Analyses of Operative Characteristics. M–H, Mantel–Haenszel; SD, standard deviation; IV, inverse variance; CI, confidence interval; df, degrees of freedom; P, probability value
Fig. 5
Fig. 5
Meta-Analyses of Postoperative Characteristics. M–H, Mantel–Haenszel; SD, standard deviation; IV, inverse variance; CI, confidence interval; df, degrees of freedom; P, probability value
See this image and copyright information in PMC

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