Monotherapy or Combination Therapy for Septic Shock? A Debate on Steroids
- PMID: 38354067
- PMCID: PMC11146543
- DOI: 10.1164/rccm.202401-0175ED
Monotherapy or Combination Therapy for Septic Shock? A Debate on Steroids
Comment on
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Effectiveness of Fludrocortisone Plus Hydrocortisone versus Hydrocortisone Alone in Septic Shock: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials.Am J Respir Crit Care Med. 2024 May 15;209(10):1219-1228. doi: 10.1164/rccm.202310-1785OC. Am J Respir Crit Care Med. 2024. PMID: 38271488 Free PMC article.
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- Venkatesh B, Finfer S, Cohen J, Rajbhandari D, Arabi Y, Bellomo R, et al. ADRENAL Trial Investigators and the Australian–New Zealand Intensive Care Society Clinical Trials Group Adjunctive glucocorticoid therapy in patients with septic shock. N Engl J Med . 2018;378:797–808. - PubMed
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- Pirracchio R, Annane D, Waschka AK, Lamontagne F, Arabi YM, Bollaert PE, et al. Patient-level meta-analysis of low-dose hydrocortisone in adults with septic shock. NEJM Evid . 2023;2:EVIDoa2300034. - PubMed
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- Teja B, Berube M, Pereira TV, Law AC, Schanock C, Pang B, et al. Effectiveness of fludrocortisone plus hydrocortisone versus hydrocortisone alone in septic shock: a systematic review and network meta-analysis of randomized controlled trials. Am J Respir Crit Care Med . 2024;209:1219–1228. - PMC - PubMed
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