Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2024 Feb 13;57(2):195-197.
doi: 10.1016/j.immuni.2024.01.016.

Host-microbial crosstalk relies on "tuft" love

Stefania De Santis  1 , Theresa T Pizarro  2
Affiliations
Free article
Comment

Host-microbial crosstalk relies on "tuft" love

Stefania De Santis et al. Immunity. .
Free article

Abstract

How commensals influence intestinal immunity is incompletely understood. In this issue of Immunity, Eshleman et al. demonstrate that microbiota-derived butyrate restrains tuft cell development via HDAC3 modulation in intestinal epithelial cells, showing how microbial metabolites impact intestinal type 2 immunity.

PubMed Disclaimer

Conflict of interest statement

Declaration of interests The authors declare no competing interests.

Comment on

References

LinkOut - more resources