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Editorial
. 2024 Jul 15;210(2):136-138.
doi: 10.1164/rccm.202401-0189ED.

Unsung Heroes? Decoding the Protective Effects of Airway Microbiota in Chronic Obstructive Pulmonary Disease

Micheál Mac Aogáin  1   2
Affiliations
Editorial

Unsung Heroes? Decoding the Protective Effects of Airway Microbiota in Chronic Obstructive Pulmonary Disease

Micheál Mac Aogáin. Am J Respir Crit Care Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
Microbiome correlates of disease status in SPIROMICS. Analysis of baseline microbiome profiles, clinical parameters, and mucin concentrations was performed in 877 participants, revealing significant microbial correlates. Longitudinal assessment of pulmonary function decline was conducted in 365 individuals, further highlighting microbial signatures associated with this clinical phenotype. Taxa associated with milder disease are illustrated as green nodes in the “eubiosis” network on the left side of the figure. These taxa potentially serve beneficial functions as integral nodes of the phylogenetically diverse eubiotic network. In contrast, microbial biomarkers indicative of disease progression and imbalance are depicted as red nodes in the “dysbiosis” network on the right, highlighting their potential role in disease pathogenesis and progression. GOLD = Global Initiative for Chronic Obstructive Lung Disease; SPIROMICS = Subpopulations and Intermediate Outcome Measures in COPD Study.
See this image and copyright information in PMC

Comment on

References

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