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Review
. 2023 Dec 31;13(4):373-380.
doi: 10.18683/germs.2023.1407. eCollection 2023 Dec.

Dental pathologies of endodontic origin and subsequent bacterial involvement - a literature review

Affiliations
Review

Dental pathologies of endodontic origin and subsequent bacterial involvement - a literature review

Alexandru Gliga et al. Germs. .

Abstract

Dental pathologies of endodontic origin are varied in nature, and include infectious and non-infectious causes. Through this review, we aim to provide a deeper understanding of the role of bacterial involvement and in the pathogenesis of endodontic pathologies, by reviewing the relevant literature on the most common bacterial species involved, and their capacity to organize as biofilms. Furthermore, we focus on the most important recent updates in the management of endodontic infections, from a multidisciplinary perspective.

Keywords: Endodontics; biofilm; dentistry; endodontic infections; root canal treatment.

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Conflict of interest statement

Conflicts of interest: All authors – none to declare.

References

    1. Miller WD. An introduction to the study of the bacterio-pathology of the dental pulp. Dent Cosmos. 1894;36:505–27.
    1. Bender IB, Seltzer S. The synergistic effect of penicillin-streptomycin and its application in the treatment of infected pulpless teeth. J Am Dent Assoc. 1950;40:169–74. doi: 10.14219/jada.archive.1950.0034. - DOI - PubMed
    1. Seltzer S, Bender IB, Christian C. Treatment of penicillin-streptomycin resistant organisms in the root canals of infected pulpless teeth. Oral Surg Oral Med Oral Pathol. 1950;3:802–6. doi: 10.1016/0030-4220(50)90278-7. - DOI - PubMed
    1. Yu C, Abbott PV. An overview of the dental pulp: its functions and responses to injury. Aust Dent J. 2007;52:S4–16. doi: 10.1111/j.1834-7819.2007.tb00525.x. - DOI - PubMed
    1. Galler KM, Weber M, Korkmaz Y, Widbiller M, Feuerer M. Inflammatory response mechanisms of the dentine-pulp complex and the periapical tissues. Int J Mol Sci. 2021;22:1480. doi: 10.3390/ijms22031480. - DOI - PMC - PubMed

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