Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Feb 17;47(1):86.
doi: 10.1007/s10143-024-02323-1.

A prospective cohort study on perioperative percutaneous balloon compression for trigeminal neuralgia: safety and efficacy analysis

Qianqian Tang  1   2 , Shihui Gao  1   2 , Changming Wang  3 , Kai Zheng  4 , Jing Zhang  2 , Haitao Huang  5 , Yanfeng Li  5 , Yi Ma  5
Affiliations

A prospective cohort study on perioperative percutaneous balloon compression for trigeminal neuralgia: safety and efficacy analysis

Qianqian Tang et al. Neurosurg Rev. .

Abstract

With the recent emergence of percutaneous balloon compression (PBC) as a promising treatment for trigeminal neuralgia (TN), there is a growing need for research on its safety and efficacy. This study was designed to evaluate the safety and efficacy of PBC in the treatment of TN patients during the perioperative period. This study involved a total of 400 TN patients who were selected and treated with PBC at our institution. The clinical data and short-term outcomes were analyzed based on sex, initial PBC treatment for TN, and subsequent PBC treatment for recurrent TN after previous PBC or microvascular decompression (MVD) or radiofrequency thermocoagulation (RFT). No statistically significant difference was found when comparing postoperative pain relief between male and female patients with TN. Nevertheless, female patients were found to be more vulnerable than male patients to abnormal facial sensations (P = 0.001), diplopia (P = 0.015), postoperative headache (P = 0.012), and hyposmia (P = 0.029). Additionally, it was observed that there was no substantial difference in the postoperative pain relief rate between the first-time PBC group and PBC for recurrent TN patients postoperatively following procedures such as PBC, MVD, and RFT. In conclusion, this study has shown that PBC treatment is effective in managing TN in both males and females, regardless of whether the treatment was administered as a primary intervention or following prior surgical procedures such as PBC, MVD, or RFT. Nonetheless, it is noted that the risk of postoperative complications appears to be higher in female patients compared to male patients.

Keywords: Efficacy; Percutaneous balloon compression; Perioperative period; Safety; Trigeminal neuralgia.

PubMed Disclaimer

References

    1. Tohyama S, Hung PS, Cheng JC, Zhang JY, Halawani A, Mikulis DJ, Oh J, Hodaie M (2020) Trigeminal neuralgia associated with a solitary pontine lesion: clinical and neuroimaging definition of a new syndrome. Pain 161(5):916–925. https://doi.org/10.1097/j.pain.0000000000001777 - DOI - PubMed - PMC
    1. Di Stefano G, Truini A, Cruccu G (2018) Current and innovative pharmacological options to treat typical and atypical trigeminal neuralgia. Drugs 78(14):1433–1442. https://doi.org/10.1007/s40265-018-0964-9 - DOI - PubMed - PMC
    1. Heinskou TB, Maarbjerg S, Wolfram F, Rochat P, Brennum J, Olesen J, Bendtsen L (2019) Favourable prognosis of trigeminal neuralgia when enrolled in a multidisciplinary management program - a two-year prospective real-life study. J Headache Pain 20(1):23. https://doi.org/10.1186/s10194-019-0973-4 - DOI - PubMed - PMC
    1. Obermann M (2010) Treatment options in trigeminal neuralgia. Ther Adv Neurol Disord 3(2):107–115. https://doi.org/10.1177/1756285609359317 - DOI - PubMed - PMC
    1. Urgosik D, Liscak R, Novotny J Jr, Vymazal J, Vladyka V (2005) Treatment of essential trigeminal neuralgia with gamma knife surgery. J Neurosurg 102:29–33. https://doi.org/10.3171/jns.2005.102.s_supplement.0029 - DOI - PubMed

LinkOut - more resources