[Adenoma of the gallbladder--pathologic analysis of 14 cases]

Abstract

Adenoma of the gallbladder is a rare benign tumor. We found fourteen in 2600 surgical specimens of cholecystectomy, an incidence of 0.55%. Three are male and eleven female Adenoma of the gallbladder is divided into two types: papilloma and tubular. Adenoma of the gallbladder might be a precancerous lesion. We found atypical hyperplasia in four and carcinomatous change in two of these fourteen adenomas. All the patients were complicated by chronic cholecystitis, and twelve by one or several stones. Chronic inflammation and the stone formation might be the etiological factors of adenoma of the gallbladder. In this paper, the histological features and differential diagnosis are discussed. We had also observed the mucinous change of this adenoma, atypical hyperplasia and carcinomatous degeneration by histochemical means.