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. 2024 Jul;79(7):1982-1988.
doi: 10.1111/all.16063. Epub 2024 Feb 19.

Airway epithelial cell cilia transcriptomic dysregulation is associated with the inflammatory phenotype in asthma

Maëva A Devilliers  1 , Audrey Brisebarre  1 , Laure M G Petit  1 , Myriam Polette  1   2 , Gaëtan Deslée  1   3 , Ratko Djukanović  4 , Valérian Dormoy  1 , Jeanne-Marie Perotin  1   3 ; U‐BIOPRED consortium
Affiliations

Airway epithelial cell cilia transcriptomic dysregulation is associated with the inflammatory phenotype in asthma

Maëva A Devilliers et al. Allergy. 2024 Jul.
No abstract available

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References

REFERENCES

    1. Heijink IH, Kuchibhotla VNS, Roffel MP, et al. Epithelial cell dysfunction, a major driver of asthma development. Allergy. 2020;75:1902‐1917.
    1. Thomas B, Rutman A, Hirst RA, et al. Ciliary dysfunction and ultrastructural abnormalities are features of severe asthma. J Allergy Clin Immunol. 2010;126:722‐729.e2.
    1. Perotin J‐M, Wheway G, Tariq K, et al. Vulnerability to acid reflux of the airway epithelium in severe asthma. Eur Respir J. 2022;60:2101634.
    1. Belgacemi R, Diabasana Z, Hoarau A, et al. Primary ciliogenesis is a crucial step for multiciliated cell determinism in the respiratory epithelium. J Cell Mol Med. 2021;25(15):7575‐7579.
    1. Perotin J‐M, Polette M, Deslée G, Dormoy V. CiliOPD: a ciliopathy‐associated COPD endotype. Respir Res. 2021;22:74.

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