HCC risk in patients who are HBeAg-positive and have chronic hepatitis B under long-term nucleos(t)ide analogue therapy: New insights from Asia

George Papatherodoridis¹, Pietro Lampertico^{2

3}

Affiliations

¹ Department of Gastroenterology, Medical School of National and Kapodistrian University of Athens, General Hospital of Athens "Laiko", Athens, Greece.
² Division of Gastroenterology and Hepatology, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
³ Department of Pathophysiology and Transplantation, CRC "A.M. and A. Migliavacca" Center for Liver Disease, University of Milan, Milan, Italy.

Editorial

George Papatherodoridis et al. Hepatology. 2024.

. 2024 Aug 1;80(2):260-262.

doi: 10.1097/HEP.0000000000000796. Epub 2024 Feb 16.

George Papatherodoridis¹, Pietro Lampertico^{2

3}

¹ Department of Gastroenterology, Medical School of National and Kapodistrian University of Athens, General Hospital of Athens "Laiko", Athens, Greece.
² Division of Gastroenterology and Hepatology, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.
³ Department of Pathophysiology and Transplantation, CRC "A.M. and A. Migliavacca" Center for Liver Disease, University of Milan, Milan, Italy.

No abstract available

Comment on

Chronic hepatitis B baseline viral load and on-treatment liver cancer risk: A multinational cohort study of HBeAg-positive patients.
Choi WM, Yip TC, Kim WR, Yee LJ, Brooks-Rooney C, Curteis T, Clark LJ, Jafry Z, Chen CH, Chen CY, Huang YH, Jin YJ, Jun DW, Kim JW, Park NH, Peng CY, Shin HP, Shin JW, Yang YH, Wong GL, Lim YS. Choi WM, et al. Hepatology. 2024 Aug 1;80(2):428-439. doi: 10.1097/HEP.0000000000000752. Epub 2024 Jan 24. Hepatology. 2024. PMID: 38436992 Free PMC article.

1. European Association for the Study of the Liver. EASL 2017 Clinical Practice Guidelines on the management of hepatitis B virus infection. J Hepatol. 2017;67:370–398.
1. Terrault NA, Lok ASF, McMahon BJ, Chang KM, Hwang JP, Jonas MM, et al. Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance. Hepatology. 2018;67:1560–1599.
1. Sarin SK, Kumar M, Lau GK, Abbas Z, Chan HL, Chen CJ, et al. Asian-Pacific clinical practice guidelines on the management of hepatitis B: A 2015 update. Hepatol Int. 2016;10:1–98.
1. Chan HL, Chan CK, Hui AJ, Chan S, Poordad F, Chang TT, et al. Effects of tenofovir disoproxil fumarate in hepatitis B e antigen-positive patients with normal levels of alanine aminotransferase and high levels of hepatitis B virus DNA. Gastroenterology. 2014;146:1240–1248.
1. Vlachogiannakos J, Papatheodoridis GV. HBV: Do I treat my immunotolerant patients? Liver Int. 2016;36(suppl. 1):93–99.