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. 2024 Jan;36(1):180-186.
doi: 10.1016/j.sdentj.2023.09.011. Epub 2023 Sep 29.

Assessing dental surgeons' understanding of bisphosphonates: Implications for patient health in oral surgery

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Assessing dental surgeons' understanding of bisphosphonates: Implications for patient health in oral surgery

Vilson Rocha Cortez Teles de Alencar et al. Saudi Dent J. 2024 Jan.

Abstract

Objectives: This study aimed to analyze the knowledge of dental surgeons concerning the pharmacological effects of bisphosphonates (BP) and their impact on the health of patients undergoing oral surgery treatment.

Materials and methods: A quantitative study was conducted with professionals in the Cariri region of Ceará, Brazil. The data were collected using a semi-structured questionnaire to interview the dental surgeons who met the inclusion criteria. The data were analyzed by Chi-square and Fischer's Exact tests using the SPSS program version 22.0.

Results: The results indicated that most interviewed subjects have no experience with the dental treatment of individuals under treatment with bisphosphonates. When a sample of the medication was presented, a significant number of the participants (65.3%) did not recognize the drug. Among those who recognized it, 66.5% did not know how to treat bisphosphonate-using patients in the clinical routine. However, 95.1% of the professionals who recognized the need to discontinue these drugs admitted contacting the prescriber to establish the best dental conduct. Our results also showed that recently graduated professionals better understood the need to stop BP use before invasive treatment, although they did not know the protocol.

Conclusion: In conclusion, a better knowledge of the pharmacological effects of BP is crucial for conducting adequate anamnesis, requesting additional tests, and performing medical monitoring, which has a significant impact on the clinical practice of dental surgeons.

Keywords: Adverse effects; Bisphosphonates; Dental surgeon; Knowledge in Brazil; Osteonecrosis.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Distribution of the study population according to the age range. Data are represented as a percentage of the total population.
Fig. 2
Fig. 2
Distribution of the study population according to the time since graduation. Data are represented as a percentage of the total population.
Fig. 3
Fig. 3
Distribution of the study population according to the work sector. Data are represented as a percentage of the total population.
Fig. 4
Fig. 4
Answers of the participants about the need to interrupt the oral use of bisphosphonates (A) and the adequate time for interruption (B).

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References

    1. Al-Hamed F.S., Mahri M., Al-Waeli H., Torres J., Badran Z., Tamimi F. Regenerative effect of platelet concentrates in oral and craniofacial regeneration. Front. Cardiovasc. Med. 2019 Sept 3;6:126. - PMC - PubMed
    1. Bagan L., Jiménez Y., Leopoldo M., Murillo-Cortes J., Bagan J. Exposed necrotic bone in 183 patients with bisphosphonate-related osteonecrosis of the jaw: Associated clinical characteristics. Med. Oral Patol. Oral Cir. Bucal. 2017 Sept 1;22(5):e582–e585. - PMC - PubMed
    1. Bermúdez-Bejarano E.B., Serrera-Figallo M.A., Gutiérrez-Corrales A., Romero-Ruiz M.M., Castillo-de-Oyagüe R., Gutiérrez-Pérez J.L., Machuca-Portillo G., Torres-Lagares D. Analysis of different therapeutic protocols for osteonecrosis of the jaw associated with oral and intravenous bisphosphonates. Med. Oral Patol. Oral Cir. Bucal. 2017 Jan 1;22(1):e43–e57. - PMC - PubMed
    1. Ferreira G.E., Pereira C.G.M., Pereira G.D., Sá G.R., Alves L.S.A., Oliveira E., Silva-Neto G.R., Bonfim M.L.C., Nobre M.C.O. Uso de bifosfonatos em idosos: complicações e condutas em odontologia. Rev. Intercâmbio. 2017;10:137–153.
    1. Fiorillo L., Cicciù M., Tözüm T.F., D’Amico C., Oteri G., Cervino G. Impact of bisphosphonate drugs on dental implant healing and peri-implant hard and soft tissues: a systematic review. BMC Oral Health. 2022;22(1):1–12. - PMC - PubMed

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