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. 2023 Oct 1;19(7):1794-1796.
doi: 10.4103/jcrt.jcrt_2052_21. Epub 2022 Sep 9.

Measurement of malignant spiculated mass lesions on mammogram: Do we include the length of the spicules?

Mohit Bhatia  1 , Rizwan Ahmed  1 , Anupama Nagarajakumar  1 , Azhar Alani  2 , Sudeendra Doddi  1 , Anna Metafa  1
Affiliations
Free article

Measurement of malignant spiculated mass lesions on mammogram: Do we include the length of the spicules?

Mohit Bhatia et al. J Cancer Res Ther. .
Free article

Abstract

Aim: The aim of this study is to determine if the core size or size with spicules has a better correlation with the final histologic size of spiculated mass lesions.

Methods: A retrospective study of 48-month duration from January 2014 to December 2017 of biopsy-proven invasive ductal carcinoma presenting as spiculated mass lesions on mammogram was conducted.

Results: There were 195 patients in the study. The mean of the core size was 16.6 mm; when spicules were included the mean size was 27.4mm and final histologic size 21.1 mm. Using unpaired Student 't' test difference in the means was statistically significant (p<0.0001). Pearson number (R) core size versus final histologic size was 0.535 (P < 0.001) and for size with spicules versus final histologic size was 0.495 (P < 0.001).

Conclusion: Our study demonstrated that the core size has a stronger positive correlation to final histologic size and should be used preoperatively in decision-making about surgery.

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References

    1. Franquet T, De Miguel C, Cozcolluela R, Donoso L. Spiculated lesions of the breast:Mammographic-pathologic correlation. Radiographics 1993;13:841–52
    1. Berment H, Becette V, Mohallem M, Ferreira F, Chérel P. Masses in mammography:What are the underlying anatomopathological lesions?. Diagn Interv Imaging 2014;95:124–33
    1. Douglas-Jones AG, Pace DP. Pathology of R4 spiculated lesions in the breast screening programme. Histopathology 1997;30:214–20
    1. Brumec M, Sobočan M, Takač I, Arko D. Clinical implications of androgen-positive triple-negative breast cancer. Cancers (Basel) 2021;13:1642
    1. Saif R, Macnair A, Kaye B. Spiculated lesions of the breast:Radiological estimate of tumour site versus pathological tumour size. How accurate is radiological measurement. EJSO 2008;34:1184

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