Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2024 Apr;38(4):908-911.
doi: 10.1038/s41375-024-02179-w. Epub 2024 Feb 20.

Germline CHEK2 mutations in patients with myeloid neoplasms

Lucie Freiman #  1   2 , Lise Larcher #  1   3   4 , Giulia Tueur  3 , Nadia Vasquez  3 , Mélanie Da Costa  3 , Matthieu Duchmann  1   3   4 , Emmanuel Raffoux  2 , Lionel Adès  1   2   4 , Pierre Fenaux  1   2   4 , Jean Soulier  1   3   4 , Nicolas Duployez  1   3   5 , Emmanuelle Clappier  1   3   4 , Marie Sébert  6   7   8
Affiliations

Germline CHEK2 mutations in patients with myeloid neoplasms

Lucie Freiman et al. Leukemia. 2024 Apr.
No abstract available

PubMed Disclaimer

References

    1. Khoury JD, Solary E, Abla O, Akkari Y, Alaggio R, Apperley JF, et al. The 5th edition of the World Health Organization Classification of Haematolymphoid Tumours: Myeloid and Histiocytic/Dendritic Neoplasms. Leukemia. 2022;36:1703–19. - DOI - PubMed - PMC
    1. Rio-Machin A, Vulliamy T, Hug N, Walne A, Tawana K, Cardoso S, et al. The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants. Nat Commun. 2020;11:1044. - DOI - PubMed - PMC
    1. Feurstein S, Trottier AM, Estrada-Merly N, Pozsgai M, McNeely K, Drazer MW, et al. Germ line predisposition variants occur in myelodysplastic syndrome patients of all ages. Blood. 2022;140:2533–48. - DOI - PubMed - PMC
    1. Bartek J, Lukas J. Chk1 and Chk2 kinases in checkpoint control and cancer. Cancer Cell. 2003;3:421–9. - DOI - PubMed
    1. Stolarova L, Kleiblova P, Janatova M, Soukupova J, Zemankova P, Macurek L, et al. CHEK2 germline variants in cancer predisposition: stalemate rather than checkmate. Cells 2020;9:2675. - DOI - PubMed - PMC

LinkOut - more resources