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Editorial
. 2024 Mar 1;52(3):512-515.
doi: 10.1097/CCM.0000000000006179. Epub 2024 Feb 21.

Mechanical Left-Ventricular Unloading in Extracorporeal Cardiopulmonary Resuscitation: A State of Clinical Equipoise

Ryan Ruiyang Ling  1 , Christopher Jer Wei Low  1 , Kollengode Ramanathan  1   2
Affiliations
Editorial

Mechanical Left-Ventricular Unloading in Extracorporeal Cardiopulmonary Resuscitation: A State of Clinical Equipoise

Ryan Ruiyang Ling et al. Crit Care Med. .
No abstract available

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Conflict of interest statement

Mr. Ling receives research support from the Clinician Scientist Development Unit, Yong Loo Lin School of Medicine, National University of Singapore. Dr. Ramanathan serves on the Steering Committee of the Extracorporeal Life Support Organisation, chairs its publication committee, and is the past co-chair of the Scientific Oversight Committee. He reports honoraria from Xenios for educational lectures on extracorporeal membrane oxygenation. Mr. Low has disclosed that he does not have any potential conflicts of interest.

Comment on

References

    1. Yannopoulos D, Bartos J, Raveendran G, et al.: Advanced reperfusion strategies for patients with out-of-hospital cardiac arrest and refractory ventricular fibrillation (ARREST): A phase 2, single centre, open-label, randomised controlled trial. Lancet. 2020; 396:1807–1816
    1. Belohlavek J, Smalcova J, Rob D, et al.; Prague OHCA Study Group: Effect of intra-arrest transport, extracorporeal cardiopulmonary resuscitation, and immediate invasive assessment and treatment on functional neurologic outcome in refractory out-of-hospital cardiac arrest: A randomized clinical trial. JAMA. 2022; 327:737–747
    1. Suverein MM, Delnoij TSR, Lorusso R, et al.: Early extracorporeal CPR for refractory out-of-hospital cardiac arrest. N Engl J Med. 2023; 388:299–309
    1. Schrage B, Becher PM, Bernhardt A, et al.: Left ventricular unloading is associated with lower mortality in patients with cardiogenic shock treated with venoarterial extracorporeal membrane oxygenation: Results from an international, multicenter cohort study. Circulation. 2020; 142:2095–2106
    1. Thevathasan T, Füreder L, Fechtner M, et al.: Left-Ventricular Unloading With Impella During Refractory Cardiac Arrest Treated With Extracorporeal Membrane Oxygenation Resucitation: A Systematic Review and Meta-Analysis. Crit Care Med. 2024; 52:464–474

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