The authors reply

Affiliations

¹ All authors: Division of Anesthesiology, Department of Anesthesiology, Pharmacology, Intensive Care and Emergency Medicine, Geneva University Hospitals, Geneva, Switzerland.

Comment

Alessandro Putzu et al. Crit Care Med. 2024.

. 2024 Mar 1;52(3):e153-e154.

doi: 10.1097/CCM.0000000000006151. Epub 2024 Feb 21.

¹ All authors: Division of Anesthesiology, Department of Anesthesiology, Pharmacology, Intensive Care and Emergency Medicine, Geneva University Hospitals, Geneva, Switzerland.

No abstract available

Conflict of interest statement

The authors have disclosed that they do not have any potential conflicts of interest.

Effect of CytoSorb on Interleukin-6.
Waalders NJB, Jansen A, Pickkers P. Waalders NJB, et al. Crit Care Med. 2024 Mar 1;52(3):e152-e153. doi: 10.1097/CCM.0000000000006120. Epub 2024 Feb 21. Crit Care Med. 2024. PMID: 38381019 No abstract available.

1. Waalders N, Jansen A, Pickkers P: Effect of CytoSorb on Interleukin-6. Crit Care Med. 2023; 51:e152–e153
1. Heymann M, Schorer R, Putzu A: The effect of CytoSorb on inflammatory markers in critically ill patients: A systematic review and meta-analysis of randomized controlled trials. Crit Care Med. 2023; 51:1659–1673
1. Jansen A, Waalders NJB, van Lier DPT, et al.: CytoSorb hemoperfusion markedly attenuates circulating cytokine concentrations during systemic inflammation in humans in vivo. Crit Care. 2023; 27:1–11
1. Heymann M, Schorer R, Putzu A: Mortality and adverse events of hemoadsorption with CytoSorb® in critically ill patients: A systematic review and meta-analysis of randomized controlled trials. Acta Anaesthesiol Scand. 2022; 66:1037–1050
1. Dellinger RP, Bagshaw SM, Antonelli M, et al.; EUPHRATES Trial Investigators: Effect of targeted polymyxin b hemoperfusion on 28-day mortality in patients with septic shock and elevated endotoxin level: The EUPHRATES randomized clinical trial. JAMA. 2018; 320:1455–1463