Phospholipid composition of guinea pig lung lavage
- PMID: 3838197
- DOI: 10.1007/BF02534355
Phospholipid composition of guinea pig lung lavage
Abstract
Phospholipids from guinea pig lung lavage were analyzed. The total lavage phospholipid content was 2.65 + 0.67 mg per gram of lung, which accounted for 85% of the total lipids in lung wash. Phosphatidylcholine (PC) accounted for over 60% of the total phospholipids. The other phospholipid fractions, in order of predominance, were phosphatidylinositol (PI), phosphatidylserine (PS), sphingomyelin (SPH), phosphatidylethanolamine (PE), phosphatidylglycerol (PG) and lysophosphatidyl-choline (LPC). Disaturated phosphatidylcholine (DSPC) comprised 80% of the total PC, and it contained mostly palmitic acid. The DSPC content of the lung lavage fluid per square meter of alveolar surface area was 5.76 +/- 0.42 mg.
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