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Case Reports
. 2024 Feb 21;11(2):e01285.
doi: 10.14309/crj.0000000000001285. eCollection 2024 Feb.

Successful Treatment of Eosinophilic Enterocolitis in an Adult Patient With Adalimumab

Yichun Fu  1 , David Choi  1 , Natali Ronen  2 , Sushila Dalal  1
Affiliations
Case Reports

Successful Treatment of Eosinophilic Enterocolitis in an Adult Patient With Adalimumab

Yichun Fu et al. ACG Case Rep J. .

Abstract

Eosinophilic gastrointestinal diseases are increasing in prevalence, but understanding of their causes and effective treatments remain elusive, especially in adults. We present a case of eosinophilic gastroenteritis and colitis with extraintestinal manifestations that was successfully treated with a tumor necrosis factor α inhibitor, adalimumab.

Keywords: anti-TNF; diarrhea; eosinophilic colitis; eosinophilic gastroenteritis.

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Figures

Figure 1.
Figure 1.
Histologic comparison of the biopsies from pre and post-treatment endoscopic evaluation. Before adalimumab treatment, there were 53 eosinophils per high-power field in the duodenum (A), 120 in the terminal ileum (C), and 87 in the colon (E). After treatment, there were 8 eosinophils per high-power field in the duodenum (B), 17 in the terminal ileum (D), and 18 in the colon (F). The insets were obtained on 400× magnification.
See this image and copyright information in PMC

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