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. 2024 May;52(4):415-425.
doi: 10.1002/jcu.23653. Epub 2024 Feb 22.

Lung ultrasound score in the decision of patent ductus arteriosus closure in neonates

Mustafa Ozdemir  1 , Tugay Tepe  1 , Ferda Ozlu  1 , Hacer Yapicioglu  1 , Anıl Atmıs  2 , Fadli Demir  2 , Ilker Unal  3 , Nejat Narli  1
Affiliations

Lung ultrasound score in the decision of patent ductus arteriosus closure in neonates

Mustafa Ozdemir et al. J Clin Ultrasound. 2024 May.

Abstract

Purpose: We aimed to investigate the role of lung ultrasound (LUS) score in the closure of hemodynamically insignificant patent ductus arteriosus (PDA) and the clinical findings of the patients before and after closure.

Methods: The study groups (107 preterm neonates under 34 gestational weeks) were classified as hemodynamically significant PDA (group 1), hemodynamically insignificant PDA with closure therapy (group 2), hemodynamically insignificant PDA without closure therapy (group 3), and no PDA group (group 4) based on the echocardiography. 6- and 10-region LUS scores were compared for each group.

Results: There was a significant difference between groups 1 and 3 on first, third, and seventh days. In contrast, groups 1 and 2 had similar LUS scores on the first, third, and seventh days. There was a negative correlation between LUS scores on the first and third days and gestational age, birth weight, the first- and fifth-minute APGAR scores, and there was a positive correlation between aortic root to left atrium ratio, and PDA diameter/weight ratio.

Conclusion: We observed that LUS scores in patients with hemodynamically insignificant PDA treated with closure therapy were similar to in patients with hemodynamically significant PDA. Thus, LUS score can have role in PDA closure in preterm neonates. However, more comprehensive studies are needed.

Keywords: lung ultrasound score; patent ductus arteriosus; prematurity; ultrasonography.

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