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. 2024 Jul;32(4):652-661.
doi: 10.1002/erv.3079. Epub 2024 Feb 22.

Let's get aligned! Developing a core outcome set for clinical trials in eating disorders

Anna Victoria Brieva-Toloza  1 , Oliver Rumle Hovmand  2   3 , Nadia Micali  1   4 , Anne Bryde Christensen  1   5
Affiliations

Let's get aligned! Developing a core outcome set for clinical trials in eating disorders

Anna Victoria Brieva-Toloza et al. Eur Eat Disord Rev. 2024 Jul.

Abstract

Objective: Our study aimed to review the outcome measures/assessment instruments used and to assess their heterogeneity/homogeneity in eating disorders (EDs) randomised controlled trials.

Methods: APA PsycInfo, PubMed, and Embase were searched in December 2022 to identify studies published between and inclusive of January 2012 and December 2022. Inclusion/exclusion criteria were: (1) complete articles published in peer-reviewed scientific journals, which were: (2) randomised trials, (3) in a clinical setting (4) with human subjects, (5) with an ICD or DSM diagnosis of Anorexia Nervosa, Binge Eating Disorder, or Bulimia Nervosa. The selected papers also: (6) used one or more standardised instruments designed to measure one or more psychometric characteristics associated with ED as a primary or secondary outcome, as judged by the authors of this systematic review, and (7) were published in English or Danish.

Results: Ninety one articles were included, and a total of 196 outcome measures were collected.

Discussion: The diversity of outcome measures in ED trials hampers result comparability and data integration. We suggest creating a core outcome measure set using the Delphi method, including clinician and patient-reported ED assessments, along with relevant comorbidity scales.

Keywords: assessment instruments; core outcome measure; eating disorder; randomised controlled trials; systematic review.

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References

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