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. 1979 May;112(1):185-9.
doi: 10.1099/00221287-112-1-185.

Studies on the interaction of Mycobacterium microti and Mycobacterium lepraemurium with mouse polymorphonuclear leucocytes

C C Smith, R M Barr, J Alexander

Studies on the interaction of Mycobacterium microti and Mycobacterium lepraemurium with mouse polymorphonuclear leucocytes

C C Smith et al. J Gen Microbiol. 1979 May.

Abstract

When polymorphonuclear leucocytes (PMN) elicited in mice were infected with Mycobacterium microti or Mycobacterium lepraemurium, phagosome-lysosome fusion occurred with both species. This contrasts with the situation in macrophages where phagosome-lysosome fusion is inhibited by M. microti but not M. lepraemurium. No evidence was found for killing of M. microti or M. lepraemurium when the bacteria were isolated from PMN and their viability tested in cell-free medium or macrophages.

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