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. 2024 Feb;29(8):2400073.
doi: 10.2807/1560-7917.ES.2024.29.8.2400073.

Clinical isolates of ST131 bla OXA-244-positive Escherichia coli, Italy, December 2022 to July 2023

Aurora Piazza  1   2 , Marta Corbella  3 , Vittoria Mattioni Marchetti  4   2 , Cristina Merla  3 , Irene Mileto  4   3 , Angela Kuka  4   3 , Greta Petazzoni  3   2 , Stefano Gaiarsa  3 , Roberta Migliavacca  1   2 , Fausto Baldanti  3   1   2 , Patrizia Cambieri  3
Affiliations

Clinical isolates of ST131 bla OXA-244-positive Escherichia coli, Italy, December 2022 to July 2023

Aurora Piazza et al. Euro Surveill. 2024 Feb.

Abstract

The dissemination of carbapenemase-producing Escherichia coli, although still at low level, should be continuously monitored. OXA-244 is emerging in Europe, mainly in E. coli. In Italy, this carbapenemase was reported from an environmental river sample in 2019. We report clinical isolates of OXA-244-producing ST131 E. coli in four patients admitted to an acute care hospital in Pavia, Italy. The association of this difficult-to-detect determinant with a globally circulating high-risk clone, ST131 E. coli, is of clinical relevance.

Keywords: Escherichia coli; OXA-244; ST131; WGS; high-risk clone; surveillance.

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Conflict of interest statement

Conflict of interest: None declared.

Figures

Figure 1
Figure 1
Heatmap representation of the virulence genes of Escherichia coli ST131 isolates, Italy, December 2022–July 2023 (n = 10)
Figure 2
Figure 2
Phylogenetic analysis of OXA-244-producing Escherichia coli ST131, Italy, December 2022–July 2023 (n = 4)
See this image and copyright information in PMC

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