The triple A model (age, absolute neutrophil count, absolute lymphocyte count-AAA) predicts survival and thrombosis in polycythemia vera

Ivan Krecak^{1

2

3}, Danijela Lekovic^{4

5}, Isidora Arsenovic⁴, Hrvoje Holik⁶, Ivan Zekanovic⁷, Martina Moric Peric⁷, Marko Lucijanic^{8

9}

Affiliations

¹ Department of Internal Medicine, General Hospital of Sibenik-Knin County, Sibenik, Croatia.
² Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
³ Undergraduate Study of Nursing, University of Applied Sciences, Sibenik, Croatia.
⁴ Clinic of Hematology, University Clinical Center of Serbia, Belgrade, Serbia.
⁵ Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
⁶ Department of Internal Medicine, Dr. Josip Benčević General Hospital, Slavonski Brod, Croatia.
⁷ Department of Internal Medicine, General Hospital Zadar, Zadar, Croatia.
⁸ Division of Hematology, University Hospital Dubrava, Zagreb, Croatia.
⁹ School of Medicine, University of Zagreb, Zagreb, Croatia.

PMID: 38391037
DOI: 10.1002/ajh.27261

Free article

Comment

The triple A model (age, absolute neutrophil count, absolute lymphocyte count-AAA) predicts survival and thrombosis in polycythemia vera

Ivan Krecak et al. Am J Hematol. 2024 May.

Free article

. 2024 May;99(5):989-992.

doi: 10.1002/ajh.27261. Epub 2024 Feb 23.

Authors

Ivan Krecak^{1

2

3}, Danijela Lekovic^{4

5}, Isidora Arsenovic⁴, Hrvoje Holik⁶, Ivan Zekanovic⁷, Martina Moric Peric⁷, Marko Lucijanic^{8

9}

Affiliations

¹ Department of Internal Medicine, General Hospital of Sibenik-Knin County, Sibenik, Croatia.
² Faculty of Medicine, University of Rijeka, Rijeka, Croatia.
³ Undergraduate Study of Nursing, University of Applied Sciences, Sibenik, Croatia.
⁴ Clinic of Hematology, University Clinical Center of Serbia, Belgrade, Serbia.
⁵ Faculty of Medicine, University of Belgrade, Belgrade, Serbia.
⁶ Department of Internal Medicine, Dr. Josip Benčević General Hospital, Slavonski Brod, Croatia.
⁷ Department of Internal Medicine, General Hospital Zadar, Zadar, Croatia.
⁸ Division of Hematology, University Hospital Dubrava, Zagreb, Croatia.
⁹ School of Medicine, University of Zagreb, Zagreb, Croatia.

PMID: 38391037
DOI: 10.1002/ajh.27261

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A globally applicable "triple A" risk model for essential thrombocythemia based on Age, Absolute neutrophil count, and Absolute lymphocyte count.
Tefferi A, Loscocco GG, Farrukh F, Szuber N, Mannelli F, Pardanani A, Hanson CA, Ketterling RP, De Stefano V, Carobbio A, Barbui T, Guglielmelli P, Gangat N, Vannucchi AM. Tefferi A, et al. Am J Hematol. 2023 Dec;98(12):1829-1837. doi: 10.1002/ajh.27079. Epub 2023 Sep 4. Am J Hematol. 2023. PMID: 37665758

References

REFERENCES

1. Barbui T, Tefferi A, Vannucchi AM, et al. Philadelphia chromosome‐negative classical myeloproliferative neoplasms: revised management recommendations from European LeukemiaNet. Leukemia. 2018;32(5):1057‐1069.
1. Tefferi A, Barbui T. Polycythemia vera: 2024 update on diagnosis, risk‐stratification, and management. Am J Hematol. 2023;98(9):1465‐1487.
1. Tefferi A, Vannucchi AM, Barbui T. Essential thrombocythemia: 2024 update on diagnosis, risk stratification, and management. Am J Hematol. 2024. Published online January 25, 2024. doi:10.1002/ajh.27216
1. Tefferi A, Guglielmelli P, Lasho TL, et al. Mutation‐enhanced international prognostic systems for essential thrombocythaemia and polycythaemia vera. Br J Haematol. 2020;189(2):291‐302.
1. Verstovsek S, Krečak I, Heidel FH, et al. Identifying patients with polycythemia vera at risk of thrombosis after hydroxyurea initiation: the polycythemia vera‐advanced integrated models (PV‐AIM) project. Biomedicine. 2023;11(7):1925.

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The triple A model (age, absolute neutrophil count, absolute lymphocyte count-AAA) predicts survival and thrombosis in polycythemia vera

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The triple A model (age, absolute neutrophil count, absolute lymphocyte count-AAA) predicts survival and thrombosis in polycythemia vera

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