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. 2024 Feb;30(2):e13621.
doi: 10.1111/srt.13621.

Reflectance confocal microscopy features of chronic radiodermatitis: A useful tool for presurgical mapping

Luca Rapparini  1   2 , Federico Venturi  1   2 , Chiara Gelati  3 , Federico Giorgini  3 , Marco Pignatti  2   3 , Michelangelo La Placa  1   2 , Biagio Scotti  1   2 , Giulia Veronesi  1   2 , Emi Dika  1   2
Affiliations

Reflectance confocal microscopy features of chronic radiodermatitis: A useful tool for presurgical mapping

Luca Rapparini et al. Skin Res Technol. 2024 Feb.
No abstract available

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Conflict of interest statement

The authors have no relevant financial or non‐financial interests to disclose.

Figures

FIGURE 1
FIGURE 1
Clinical and dermoscopic presentation of radiodermatitis: clinical examination showed an erythematous macule surmounted by a large crusted, fibrinous plaque (A). Dermoscopy revealed an atypical vascular pattern characterized by large vessels at the periphery of the central keratin mass (B).
FIGURE 2
FIGURE 2
RCM features of radiodermitis revealed, at the level of the stratum corneum, a severely disrupted corneal layer with presence of parakeratoses and detached corneocytes, whereas at the level of the stratum granulosum we observed areas of necrosis corresponding to dark spaces with irregular demarcation and pronounced disruption of the epidermal architecture. Surrounding keratinocytes displayed the presence of spongiosis, seen as increased brightness of intercellular spaces, accentuating the honeycombed pattern of the granular layer (A). Due to the presence of severe photodamage, RCM was performed also contralaterally on the left mammary skin, which displayed an irregular epidermal honeycomb pattern with curled collagen in the dermis (B).
See this image and copyright information in PMC

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