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Review
. 2024 Feb 18;14(2):108.
doi: 10.3390/bios14020108.

Hierarchical Nanobiosensors at the End of the SARS-CoV-2 Pandemic

Jael Abigail Medrano-Lopez  1 , Isaela Villalpando  2 , Ma Isabel Salazar  3 , Carlos Torres-Torres  1
Affiliations
Review

Hierarchical Nanobiosensors at the End of the SARS-CoV-2 Pandemic

Jael Abigail Medrano-Lopez et al. Biosensors (Basel). .

Abstract

Nanostructures have played a key role in the development of different techniques to attack severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Some applications include masks, vaccines, and biosensors. The latter are of great interest for detecting diseases since some of their features allowed us to find specific markers in secretion samples such as saliva, blood, and even tears. Herein, we highlight how hierarchical nanoparticles integrated into two or more low-dimensional materials present outstanding advantages that are attractive for photonic biosensing using their nanoscale functions. The potential of nanohybrids with their superlative mechanical characteristics together with their optical and optoelectronic properties is discussed. The progress in the scientific research focused on using nanoparticles for biosensing a variety of viruses has become a medical milestone in recent years, and has laid the groundwork for future disease treatments. This perspective analyzes the crucial information about the use of hierarchical nanostructures in biosensing for the prevention, treatment, and mitigation of SARS-CoV-2 effects.

Keywords: SARS-CoV-2; biosensors; detection limit; hierarchical nanostructures; nanoparticles.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Representative characteristics exhibited by different nanostructures in biosensing applications.
Figure 2
Figure 2
Representative processing routes for the synthesis of hierarchical nanostructures used in the development of biosensors.
Figure 3
Figure 3
Typical techniques for measurements using nanostructured biosensors.
Figure 4
Figure 4
Representative characteristics exhibited by different types of nanostructures.
Figure 5
Figure 5
Different types of hierarchical structures for the development of biosensors.
See this image and copyright information in PMC

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