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. 2024 Jan 29;14(2):149.
doi: 10.3390/jpm14020149.

Decrease in Mortality after the Implementation of a Hospital Model to Improve Performance in Sepsis Care: Princess Sepsis Code

Rosa Méndez  1 , Angels Figuerola  2 , Fernando Ramasco  1 , Marta Chicot  3 , Natalia F Pascual  4 , Íñigo García  5 , Andrés von Wernitz  6 , Nelly D Zurita  7 , Auxiliadora Semiglia  7 , Alberto Pizarro  6 , Carmen Saez  8 , Diego Rodríguez  9
Affiliations

Decrease in Mortality after the Implementation of a Hospital Model to Improve Performance in Sepsis Care: Princess Sepsis Code

Rosa Méndez et al. J Pers Med. .

Abstract

Sepsis is a time-dependent disease whose prognosis is influenced by early diagnosis and therapeutic measures. Mortality from sepsis remains high, and for this reason, the guidelines of the Surviving Sepsis Campaign recommend establishing specific care programs aimed at patients with sepsis. We present the results of the application of a hospital model to improve performance in sepsis care, called Princess Sepsis Code, with the aim of reducing mortality. A retrospective study was conducted using clinical, epidemiological, and outcome variables in patients diagnosed with sepsis from 2015 to 2022. A total of 2676 patients were included, 32% of whom required admission to the intensive care unit, with the most frequent focus of the sepsis being abdominal. Mortality in 2015, at the beginning of the sepsis code program, was 24%, with a declining rate noted over the study period, with mortality reaching 17% in 2022. In the multivariate analysis, age > 70 years, respiratory rate > 22 rpm, deterioration in the level of consciousness, serum lactate > 2 mmol/L, creatinine > 1.6 mg/dL, and the focus of the sepsis were identified as variables independently related to mortality. The implementation of the Princess Sepsis Code care model reduces the mortality of patients exhibiting sepsis and septic shock.

Keywords: intensive care units; mortality; qSOFA; sepsis; sepsis code; septic shock.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
Princess Sepsis Code logo.
Figure 2
Figure 2
Action algorithm of the Princess Sepsis Code.
Figure 3
Figure 3
Location of the origin of sepsis infection.
Figure 4
Figure 4
Evolution of percentage of mortality throughout the years of the study.
Figure 5
Figure 5
Mortality according to SOFA group and activation department.
See this image and copyright information in PMC

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