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Review
. 2024 Jan 31;14(2):165.
doi: 10.3390/jpm14020165.

Psoriasis and Fibromyalgia: A Systematic Review

Martina D'Onghia  1 , Francesco Ursini  2   3 , Elisa Cinotti  1 , Laura Calabrese  1 , Linda Tognetti  1 , Alessandra Cartocci  1 , Laura Lazzeri  1 , Bruno Frediani  4 , Pietro Rubegni  1 , Emanuele Trovato  1
Affiliations
Review

Psoriasis and Fibromyalgia: A Systematic Review

Martina D'Onghia et al. J Pers Med. .

Abstract

Psoriasis is a chronic inflammatory cutaneous condition characterized by several comorbidities, including musculoskeletal disorders. While the association with psoriatic arthritis has been widely addressed in literature, the aim of the present systematic review was to identify all available evidence on the relationship between psoriasis and fibromyalgia, a musculoskeletal syndrome primarily characterized by chronic widespread pain. We followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, and MedLine and Web of Science (WOS) databases were searched for literature up to March 2023. After the removal of duplicate records, a total of 11 articles were deemed eligible for inclusion in a qualitative synthesis. Our results suggested that psoriatic patients had a higher prevalence of fibromyalgia (8-30%), with a very high impact on symptoms of psoriasis. Moreover, fibromyalgic patients had a slightly increased prevalence of psoriasis (2.2-6.7%) compared to the control groups. Finally, several studies demonstrated the substantial impact of fibromyalgia on psoriatic outcome measures in patients with concomitant psoriatic arthritis. In conclusion, available data support a potential interplay between psoriasis and fibromyalgia, but further research is encouraged in this area.

Keywords: fibromyalgia; psoriasis; systematic review.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
PRISMA—compliant study selection flow chart.
See this image and copyright information in PMC

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