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. 2024 Feb 15;13(2):176.
doi: 10.3390/pathogens13020176.

Mapping the Silent Threat: A Comprehensive Analysis of Chagas Disease Occurrence in Riverside Communities in the Western Amazon

Daniela da Silva Paixão  1 , Fernanda Portela Madeira  1   2 , Adila Costa de Jesus  1   2 , Hêmilly Caroline da Silva Paixão  3 , Juliana de Souza Almeida Aranha Camargo  4 , Mariane Albuquerque Lima Ribeiro  1   5 , Leandro José Ramos  5 , Jader de Oliveira  3   6 , João Aristeu da Rosa  7 , Paulo Sérgio Bernarde  1   2 , Antonieta Pereira Relvas  8 , Sergio de Almeida Basano  4 , Luis Marcelo Aranha Camargo  4   9 , Dionatas Ulises de Oliveira Meneguetti  1   3   10
Affiliations

Mapping the Silent Threat: A Comprehensive Analysis of Chagas Disease Occurrence in Riverside Communities in the Western Amazon

Daniela da Silva Paixão et al. Pathogens. .

Abstract

Chagas disease (CD) is a typical tropical illness caused by Trypanosoma cruzi. The objective of this study was to assess the prevalence of Chagas disease in communities in two states of the Brazilian Amazon. Data collection occurred in July in the Alto Juruá region of Acre and in December in the communities of Humaitá, Amazonas, in 2019. A total of 477 participants were included in the study. In the communities of Alto Juruá, triatomine collections and analyses of T. cruzi infection were also carried out. All confirmed cases were found in the state of Acre, resulting in a total prevalence of 1.67. Of these eight cases, seven underwent ECG, all of which were concluded as normal by the physician team's cardiologists. Seventeen triatomine bugs, all belonging to the Rhodnius genus, were captured. The natural infection rate by T. cruzi was 25% in the Nova Cintra community and 66.67% in the Boca do Moa community (Alto Juruá). This research found that more than 1% of the studied population exhibited positive serological results for Chagas disease in the riverine communities during the study period, representing a small portion of cases among those who have not yet been diagnosed.

Keywords: American Trypanosomiasis; Trypanosoma cruzi and Amazônia; vectors.

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Conflict of interest statement

The authors declare no conflicts of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript; or in the decision to publish the results.

Figures

Figure 1
Figure 1
Map of the study areas with the following descriptions: (A) Nova Cintra Community in the municipality of Cruzeiro do Sul, Acre, Brazil; (B) Boca do Moa Community in the municipality of Rodrigues Alves, Acre, Brazil; (C) Humaitá Communities, Amazonas, Brazil.
Figure 2
Figure 2
Collections in the Boca do Moa community, Cruzeiro do Sul, Acre, Brazil. (A) First day of collections at a local church; (B) realization of ECG; (C) second day of collections carried out at a daycare center; (D) preparation of slides and material for serology.
Figure 3
Figure 3
Collection in riverside communities of Humaitá, Amazonas, Brazil. (A) House in the Tabuleta community; (B) school in the Carará community; (C) church in the Creole community; (D) boats used to visit other communities.
Figure 4
Figure 4
Electrocardiogram of three patients with chronic Chagas disease. (A) Female patient, 50 years old; (B) female patient, 16 years old; (C) female patient, 30 years old.
See this image and copyright information in PMC

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