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Review
. 2024 Jan 24;22(2):59.
doi: 10.3390/md22020059.

Diversified Chemical Structures and Bioactivities of the Chemical Constituents Found in the Brown Algae Family Sargassaceae

Yan Peng  1 , Xianwen Yang  2 , Riming Huang  3 , Bin Ren  1 , Bin Chen  1 , Yonghong Liu  4 , Hongjie Zhang  5
Affiliations
Review

Diversified Chemical Structures and Bioactivities of the Chemical Constituents Found in the Brown Algae Family Sargassaceae

Yan Peng et al. Mar Drugs. .

Abstract

Sargassaceae, the most abundant family in Fucales, was recently formed through the merging of the two former families Sargassaceae and Cystoseiraceae. It is widely distributed in the world's oceans, notably in tropical coastal regions, with the exception of the coasts of Antarctica and South America. Numerous bioactivities have been discovered through investigations of the chemical diversity of the Sargassaceae family. The secondary metabolites with unique structures found in this family have been classified as terpenoids, phlorotannins, and steroids, among others. These compounds have exhibited potent pharmacological activities. This review describes the new discovered compounds from Sargassaceae species and their associated bioactivities, citing 136 references covering from March 1975 to August 2023.

Keywords: Fucales; Sargassaceae; bioactivity; brown algae; secondary metabolites.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 4
Figure 4
Norditerpenoids isolated from Sargassacean species.
Figure 5
Figure 5
C-12 oxidized linear diterpenoids isolated from Sargassacean species.
Figure 6
Figure 6
C-13 oxidized linear diterpenoids isolated from Sargassacean species.
Figure 7
Figure 7
Non C-12/C-13 oxidized linear diterpenoids isolated from Sargassacean species.
Figure 8
Figure 8
Hydroazulene diterpenes isolated from Sargassacean species.
Figure 9
Figure 9
Xenicane diterpenes isolated from Sargassacean species.
Figure 11
Figure 11
Terpenyl-quinones/hydroquinones isolated from Sargassacean species.
Figure 11
Figure 11
Terpenyl-quinones/hydroquinones isolated from Sargassacean species.
Figure 11
Figure 11
Terpenyl-quinones/hydroquinones isolated from Sargassacean species.
Figure 12
Figure 12
Chromene meroterpenoids isolated from Sargassacean species.
Figure 13
Figure 13
Nahocol/isonahocol meroterpenoids isolated from Sargassacean species.
Figure 14
Figure 14
Monomeric phloroglucinols isolated from Sargassacean species.
Figure 15
Figure 15
Phloroglucinol derivatives belonging to the class of fucophlorethols.
Figure 15
Figure 15
Phloroglucinol derivatives belonging to the class of fucophlorethols.
Figure 16
Figure 16
Phloroglucinol derivatives belonging to the class of hydroxyphlorethols.
Figure 17
Figure 17
Phloroglucinol derivatives belonging to the class of carmalols.
Figure 18
Figure 18
Phloroglucinol derivatives belonging to the class of phlorethofuhalols.
Figure 19
Figure 19
Phloroglucinol derivatives belonging to the class of fuhalols and others.
Figure 20
Figure 20
Steroids isolated from the family Sargassaceae.
Figure 21
Figure 21
Other types of compounds isolated from Sargassacean species.
Figure 1
Figure 1
Some Sargassacean species.
Figure 2
Figure 2
Monoterpenoids isolated from Sargassacean species.
Figure 3
Figure 3
Sesquiterpenoids isolated from Sargassacean species.
Figure 10
Figure 10
Nor-dammarane triterpenoids isolated from Sargassacean species.
Figure 22
Figure 22
Distribution of compounds from Sargassacean species.
Figure 23
Figure 23
Numbers of compounds and publications from Sargassacean genus.
See this image and copyright information in PMC

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