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Editorial
. 2024 Apr 1;209(7):774-776.
doi: 10.1164/rccm.202402-0340ED.

Treatment Mechanism and Inflammatory Subphenotyping in Acute Respiratory Distress Syndrome

Alexis L Serra  1 , Nuala J Meyer  2 , Jeremy R Beitler  1
Affiliations
Editorial

Treatment Mechanism and Inflammatory Subphenotyping in Acute Respiratory Distress Syndrome

Alexis L Serra et al. Am J Respir Crit Care Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
Several factors may influence the effect of neuromuscular blockade on survival and recovery in acute respiratory distress syndrome. Molecular subphenotypes capture a degree of systemic inflammation but do not consider factors linked directly to treatment mechanism, such as patient self-inflicted lung injury and diaphragm injury. Neuromuscular blockade requires deep sedation, which itself can modify clinical outcomes. Other potential factors may include the degree of lung and endothelial injury, the extent of multiorgan dysfunction, body composition, and chronic morbidities, any of which might contribute to heterogeneity of treatment effect. Figure created with BioRender.com. PSILI = patient self-inflicted lung injury.
See this image and copyright information in PMC

Comment on

References

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