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. 1985;70(4):337-40.
doi: 10.1007/BF00295373.

Assignment of human pepsinogen A locus to the q12-pter region of chromosome 11

B Zelle, A Geurts van Kessel, J de Wit, P Evers, F Arwert, J C Pronk, W H Mager, R J Planta, A W Eriksson, R R Frants

Assignment of human pepsinogen A locus to the q12-pter region of chromosome 11

B Zelle et al. Hum Genet. 1985.

Abstract

A 0.9kb cDNA fragment, corresponding to a large part of Rhesus monkey pepsinogen A mRNA, was used as probe for the chromosomal localization of the human pepsinogen A gene(s) using human-rodent somatic cell hybrids. Southern blot analysis of 14 human-Chinese hamster and three human-mouse cell hybrids, strongly indicates that the human PGA locus is on chromosome 11. The human-mouse hybrids, containing a translocation involving chromosome 11, allow sublocalization to the region q12-pter.

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