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. 1979:(27):587-91.

Endometrial histology and post-partum mares treated with progesterone and synthetic GnRH (AY-24,031)

A M Pope, D L Campbell, J P Davidson
  • PMID: 383989

Endometrial histology and post-partum mares treated with progesterone and synthetic GnRH (AY-24,031)

A M Pope et al. J Reprod Fertil Suppl. 1979.

Abstract

Foal heat was significantly delayed in 15 Thoroughbred and Quarter-horse mares by 200 mg progesterone in oil from Days 5--14 post partum. Nine of these mares subsequently received daily i.v. injections of 2 mg of a synthetic GnRH preparation (AY-24,031) from Day 2 of the progesterone-delayed oestrus but this treatment did not significantly shorten oestrus or hasten ovulation. Uterine biopsies taken on Day 15 post partum from all the mares showed a mixed endometrial morphology having both oestrous and dioestrous characteristics. There was an increased proliferation of endometrial glands in these animals at the time of ovulation compared to control mares having a normal foal heat.

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