Comparative Study
doi: 10.1016/0006-8993(85)91490-8.
Peptide YY (PYY), a potent orexigenic agent
- PMID: 3840047
- DOI: 10.1016/0006-8993(85)91490-8
Item in Clipboard
Comparative Study
Peptide YY (PYY), a potent orexigenic agent
Brain Res.
.
Abstract
Peptide YY (PYY) enhances feeding and drinking more potently than does neuropeptide Y after central administration. Chronic administration of PYY every 6 h for 48 h causes massive food ingestion. Tolerance to this effect of PYY does not appear to develop. This data suggests that PYY is one of the most potent orexigenic substances yet to be identified. PYY may play a role in the pathogenesis of bulimic syndromes.
Similar articles
-
Effect of fourth ventricular neuropeptide Y and peptide YY on ingestive and other behaviors.Am J Physiol. 1990 Aug;259(2 Pt 2):R317-23. doi: 10.1152/ajpregu.1990.259.2.R317. Am J Physiol. 1990. PMID: 2386243
-
Paraventricular nucleus injections of peptide YY and neuropeptide Y preferentially enhance carbohydrate ingestion.Peptides. 1985 Nov-Dec;6(6):1205-11. doi: 10.1016/0196-9781(85)90452-8. Peptides. 1985. PMID: 3841735
-
Blockade of the neuropeptide Y Y2 receptor with the specific antagonist BIIE0246 attenuates the effect of endogenous and exogenous peptide YY(3-36) on food intake.Brain Res. 2005 May 10;1043(1-2):139-44. doi: 10.1016/j.brainres.2005.02.065. Brain Res. 2005. PMID: 15862527
-
Peptide YY: a key mediator of orexigenic behavior.Peptides. 2002 Feb;23(2):377-82. doi: 10.1016/s0196-9781(01)00614-3. Peptides. 2002. PMID: 11825652 Review.
-
Peptide YY(1-36) and peptide YY(3-36): Part I. Distribution, release and actions.Obes Surg. 2006 May;16(5):651-8. doi: 10.1381/096089206776944959. Obes Surg. 2006. PMID: 16687037 Review.
Cited by
-
Gut hormones ghrelin, PYY, and GLP-1 in the regulation of energy balance [corrected] and metabolism.Endocrine. 2006 Feb;29(1):61-71. doi: 10.1385/endo:29:1:61. Endocrine. 2006. PMID: 16622293 Review.
-
Gut microbes and food reward: From the gut to the brain.Front Neurosci. 2022 Jul 25;16:947240. doi: 10.3389/fnins.2022.947240. eCollection 2022. Front Neurosci. 2022. PMID: 35958993 Free PMC article. Review.
-
Bariatric surgery for extreme adolescent obesity: indications, outcomes, and physiologic effects on the gut-brain axis.Pathophysiology. 2008 Aug;15(2):135-46. doi: 10.1016/j.pathophys.2008.04.005. Epub 2008 Jun 27. Pathophysiology. 2008. PMID: 18585904 Free PMC article.
-
Can Bayliss and Starling gut hormones cure a worldwide pandemic?J Physiol. 2014 Dec 1;592(23):5153-67. doi: 10.1113/jphysiol.2014.272955. Epub 2014 Sep 12. J Physiol. 2014. PMID: 25217372 Free PMC article.
-
Obesity and appetite control.Exp Diabetes Res. 2012;2012:824305. doi: 10.1155/2012/824305. Epub 2012 Aug 1. Exp Diabetes Res. 2012. PMID: 22899902 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
