doi: 10.1016/0304-3940(85)90331-3.
Reduced sleep in cats after intraperitoneal injection of delta-sleep-inducing peptide (DSIP)
- PMID: 3840239
- DOI: 10.1016/0304-3940(85)90331-3
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Reduced sleep in cats after intraperitoneal injection of delta-sleep-inducing peptide (DSIP)
Neurosci Lett.
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Abstract
The effect of intraperitoneally injected delta-sleep-inducing peptide (DSIP) on sleep-wakefulness in cats was studied using EEG, EMG and EOG recording for 10 h following 30 nmol/kg DSIP or control saline i.p. injections. DSIP reduced the amount of sleep, specifically light slow-wave sleep and REM sleep, and REM sleep latency was increased. The results suggest that in cats with redundancy sleep DSIP increases wakefulness at the cost of light slow-wave sleep, and in addition it has a specific REM-reducing effect.
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