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Comment
. 2024 May;9(5):402-405.
doi: 10.1016/S2468-1253(23)00406-5. Epub 2024 Feb 22.

Use of immunomodulators in combination with infliximab in Crohn's disease: time for a reappraisal?

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Comment

Use of immunomodulators in combination with infliximab in Crohn's disease: time for a reappraisal?

Thomas P Chapman et al. Lancet Gastroenterol Hepatol. 2024 May.
No abstract available

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Conflict of interest statement

TPC has received educational support from Janssen and Dr Falk Pharma (UK), speaker fees from Janssen, Dr Falk Pharma (UK), and Tillotts Pharma, and consulting fees from Techspert, IQVIA, and Sermo. TA has received educational support from Celltrion Healthcare and Tillotts Pharma, speaker fees from F Hoffmann-La Roche, Pfizer, and Takeda, consulting fees from Amgen, Celltrion Healthcare, Janssen, and Eli Lilly, unrestricted grants from Celltrion Healthcare, Biogen, Nova Pharmaceuticals, Galapagos, Takeda, and Pfizer, and equipment, materials, drugs, medical writing, gifts, or other services from F Hoffmann-La Roche and MAST Group. JS plans a patent application to develop a non-immunogenic anti-TNF biological agent, is director of the UK Inflammatory Bowel Disease Registry, and has received consulting fees from Janssen, grants to Oxford University from the European Community, European Crohn's and Colitis Organisation, Helmsley Trust, Action Medical Research, and Crohn's and Colitis UK.

Comment on

  • Infliximab, azathioprine, or combination therapy for Crohn's disease.
    Colombel JF, Sandborn WJ, Reinisch W, Mantzaris GJ, Kornbluth A, Rachmilewitz D, Lichtiger S, D'Haens G, Diamond RH, Broussard DL, Tang KL, van der Woude CJ, Rutgeerts P; SONIC Study Group. Colombel JF, et al. N Engl J Med. 2010 Apr 15;362(15):1383-95. doi: 10.1056/NEJMoa0904492. N Engl J Med. 2010. PMID: 20393175 Clinical Trial.

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