Recurrent Periprosthetic Joint Infections: Diagnosis, Management, and Outcomes

Abstract

Periprosthetic joint infection (PJI) remains one of the most common complications after total joint arthroplasty. It is challenging to manage, associated with significant morbidity and mortality, and is a financial burden on the health care system. Failure of 2-stage management for chronic PJI is not uncommon. Repeat infections are oftentimes polymicrobial, multiple drug-resistant microorganisms, or new organisms. Optimizing the success of index 2-stage revision is the greatest prevention against failure of any subsequent management options and requires a robust team-based approach.

Keywords: Arthroplasty; Infected total joint arthroplasty; Persistant infection; Prosthetic joint infection; Recurrent infection.