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. 2023 Dec 19;5(1):278-279.
doi: 10.1002/jha2.834. eCollection 2024 Feb.

Erythroblastic islands: A fertile ground for CD47 expression in myelodysplastic syndrome and acute erythroid leukaemia

Sophie Le Grand  1 , Christian Récher  1 , Alban Canali  2 , Véronique De Mas  2 , Jean-Baptiste Rieu  2
Affiliations

Erythroblastic islands: A fertile ground for CD47 expression in myelodysplastic syndrome and acute erythroid leukaemia

Sophie Le Grand et al. EJHaem. .
No abstract available

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Conflict of interest statement

The authors declare they have no conflicts of interest.

Figures

FIGURE 1
FIGURE 1
Left images: Bone marrow examination at the time of myelodysplastic syndrome (MDS) diagnosis, May–Grünwald–Giemsa, 100× objective. Marked dyserythropoiesis with gigantism, nuclear budding and multinuclearity (upper left image). Erythroblastic island consisting of proerythroblasts and early to late erythroblasts surrounding a central macrophage (lower left image). Centre images: Bone marrow examination at the time of acute erythoid leukaemia (AEL) diagnosis, May–Grünwald–Giemsa, 100× objective. Atypical immature proerythroblasts (upper centre image). Erythroblastic island consisting of atypical immature proerythroblasts surrounding a central macrophage (lower centre image). Right images: Flow cytometric immunophenotyping in bone marrow sample showing CD34– CD235a+ atypical immature proerythroblasts (upper right image, in green) and CD34+ CD235a– myeloblasts (upper right image, in red) with an increased CD47 expression in atypical immature proerythroblasts (lower right image, in green).
See this image and copyright information in PMC

References

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