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. 2024 Feb 25;196(7):E242.
doi: 10.1503/cmaj.230555-f.

Hypothyroïdie causée par l’apalutamide

[Article in French]
Quinn Daviduck  1 , Scott North  1 , Rukia Swaleh  2
Affiliations

Hypothyroïdie causée par l’apalutamide

[Article in French]
Quinn Daviduck et al. CMAJ. .
No abstract available

PubMed Disclaimer

Conflict of interest statement

Intérêts concurrents: Scott North déclare avoir reçu des honoraires de consultation de la société Janssen. Aucun autre intérêt concurrent n’a été déclaré.

References

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    1. Chi KN, Agarwal N, Bjartell A, et al. TITAN Investigators. Apalutamide for metastatic, castration-sensitive prostate cancer. N Engl J Med 2019;381:13–24. - PubMed
    1. ERLEADA (apalutamide) tablets. Horsham (PA): Janssen Products; 2019, révisé février 2023. Accessible ici: https://www.janssenlabels.com/package-insert/product-monograph/prescribi... (consulté le 14 sept. 2023).
    1. Moffat C, Shen J, Drakaki A, et al. Apalutamide as an emerging cause of hypothyroidism in prostate cancer patients: a case series. Thyroid 2022;32:A54.
    1. Richardson TA, Klassen CD. Role of UDP-glucuronosyltransferase (UGT) 2B2 in metabolism of triiodothyronine: effect of microsomal enzyme inducers in Sprague Dawley and UGT2B2-deficient Fischer 344 rats. Toxicol Sci 2010;116:413–21. - PMC - PubMed