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. 2024 Feb 26;25(1):70.
doi: 10.1186/s12882-024-03492-3.

Gender disparities in kidney replacement therapies and transplantation in Colombia

Affiliations

Gender disparities in kidney replacement therapies and transplantation in Colombia

Laura Nino-Torres et al. BMC Nephrol. .

Abstract

Background: In chronic kidney disease (CKD), there are historical inequities in multiple stages of the pathway for organ transplantation. Women have been recognized as disadvantaged within this process even after several efforts. Therefore, we aimed to analyze the prevalence and incidence of CKD by gender and their access to Kidney replacement therapy (KRT) in Colombia.

Methods: A cross-sectional study based on secondary analysis of national information on CKD, hypertension, diabetes, waiting list, deceased, and living donor transplantation between 2015 and 2020.

Results: In Colombia, 4.934.914 patients were diagnosed with hypertension, diabetes, or CKD. 60,64% were female, with a mean age of 63.84 years (SD 14,36). Crude incidence for hypertension (10.85 vs. 7.21 /1000 inhabitants), diabetes mellitus (3.77 vs. 2.98 /1000 inhabitants), and CKD (4 vs. 2 /1000 inhabitants) was higher for females. Crude incidence for KRT was 86.45 cases /100.0000 inhabitants. In 2020, 2978 patients were on the waiting list, 44% female. There were 251 deaths on the waiting list, 38% female. This year, 517 kidney transplants were performed, and only 40% were female.

Conclusion: In Colombia, there are proportionally more females with CKD and precursor comorbidities. Nevertheless, there are fewer females on the waiting list and transplanted annually.

Keywords: CKD; Diabetes; Gender disparity; Organ transplantation; Renal replacement therapy.

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Conflict of interest statement

The authors declare no competing interests.

Figures

Fig. 1
Fig. 1
Chronic arterial hypertension incidence and prevalence in Colombia 2015–2020
Fig. 2
Fig. 2
Incidence and prevalence of diabetes mellitus in Colombia 2015-2020
Fig. 3
Fig. 3
CKD incidence and prevalence in Colombia, 2015–2020
Fig. 4
Fig. 4
Incidence and prevalence of ESKD in Colombia, 2015–2020
Fig. 5
Fig. 5
Prevalence of KRT in Colombia, 2015–2020
Fig. 6
Fig. 6
Patients indicated, and contraindicated for kidney transplantation in Colombia, 2015–2020
Fig. 7
Fig. 7
Kidney donors in Colombia 2020
Fig. 8
Fig. 8
Kidney transplantation in Colombia 2017–2020
Fig. 9
Fig. 9
General characteristics by sex of the population in the CKD pathway
Fig. 10
Fig. 10
Mortality in KT patients in Colombia 2015–2020
Fig. 11
Fig. 11
Identified barriers in KT

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