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Review
. 2024 Mar;84(3):363-368.
doi: 10.1007/s40265-024-02012-9.

Berdazimer Topical Gel, 10.3%: First Approval

Susan J Keam  1
Affiliations
Review

Berdazimer Topical Gel, 10.3%: First Approval

Susan J Keam. Drugs. 2024 Mar.

Abstract

Berdazimer topical gel, 10.3% (ZELSUVMI™) is a nitric oxide (NO) releasing topical gel developed by Novan Inc. (a Ligand Pharmaceuticals company) for the treatment of molluscum contagiosum (MC). Novan has used their proprietary NO-based technology platform (NITRICIL™), which stores gaseous NO species on large polymers, in the development of berdazimer topical gel, 10.3%. In January 2024, berdazimer topical gel, 10.3% was approved for the topical treatment of MC in adult and paediatric patients 1 year of age and older in the USA. This article summarizes the milestones in the development of berdazimer topical gel, 10.3% leading to this first approval for the treatment of MC.

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References

    1. Eichenfield L, Hebert A, Mancini A, et al. Therapeutic approaches and special considerations for treating molluscum contagiosum. J Drugs Dermatol. 2021;20(11):1185–90. - DOI - PubMed
    1. Lacarrubba F, Micali G, Trecarichi AC, et al. New developing treatments for molluscum contagiosum. Dermatol Ther (Heidelb). 2022;12(12):2669–78. - DOI - PubMed - PMC
    1. Olsen JR, Gallacher J, Finlay AY, et al. Time to resolution and effect on quality of life of molluscum contagiosum in children in the UK: a prospective community cohort study. Lancet Infect Dis. 2015;15(2):190–5. - DOI - PubMed
    1. Oza VS. Molluscum contagiosum therapeutics—new options may be around the corner. JAMA Dermatol. 2022;158(8):863–4. - DOI - PubMed
    1. US Food & Drug Administration. FDA approves first treatment for molluscum contagiosum [media release]. 24 Jul 2023. https://www.fda.gov/ .

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