Biphenomycins A and B, novel peptide antibiotics. II. Structural elucidation of biphenomycins A and B
- PMID: 3841123
- DOI: 10.7164/antibiotics.38.1462
Biphenomycins A and B, novel peptide antibiotics. II. Structural elucidation of biphenomycins A and B
Abstract
The structures of biphenomycins A and B, novel peptide antibiotics produced by a strain of Streptomyces, have been established as 1 and 2, respectively, on the basis of spectroscopic and chemical evidence. They are unique in that they are cyclic peptides containing a biphenyl moiety included in a 15-membered ring and show potent antibacterial activities especially against Gram-positive bacteria.
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