Asian Pacific Association for the Study of the Liver clinical practice guidelines on liver transplantation

doi:10.1007/s12072-023-10629-3

Practice Guideline

. 2024 Apr;18(2):299-383.

doi: 10.1007/s12072-023-10629-3. Epub 2024 Feb 28.

Asian Pacific Association for the Study of the Liver clinical practice guidelines on liver transplantation

Dong-Sik Kim¹, Young-In Yoon², Beom Kyung Kim³, Ashok Choudhury⁴, Anand Kulkarni⁵, Jun Yong Park³, Jongman Kim⁶, Dong Hyun Sinn⁷, Dong Jin Joo⁸, YoungRok Choi⁹, Jeong-Hoon Lee¹⁰, Ho Joong Choi¹¹, Ki Tae Yoon¹², Sun Young Yim¹³, Cheon-Soo Park¹⁴, Deok-Gie Kim⁸, Hae Won Lee¹⁵, Won-Mook Choi¹⁶, Young Eun Chon¹⁷, Woo-Hyoung Kang², Jinsoo Rhu⁶, Jae Geun Lee⁸, Yuri Cho¹⁸, Pil Soo Sung¹⁹, Han Ah Lee²⁰, Ji Hoon Kim¹³, Si Hyun Bae¹⁹, Jin Mo Yang²¹, Kyung-Suk Suh²², Mamun Al Mahtab²³, Soek Siam Tan²⁴, Zaigham Abbas²⁵, Ananta Shresta²⁶, Shahinul Alam²⁷, Anil Arora²⁸, Ashish Kumar²⁸, Pravin Rathi²⁹, Ruveena Bhavani³⁰, Charles Panackel³¹, Kuei Chuan Lee³², Jun Li³³, Ming-Lung Yu³⁴, Jacob George³⁵, Tawesak Tanwandee³⁶, Sen-Yung Hsieh³⁷, Chee Chien Yong³⁷, Mohamed Rela³⁸, H C Lin³⁹, Masao Omata^{40

41}, Shiv Kumar Sarin⁴; for Asian Pacific Association for Study of Liver (APASL)

Affiliations

¹ Department of Surgery, Korea University College of Medicine, Seoul, Republic of Korea.
² Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
³ Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
⁴ Institute of Liver and Biliary Sciences, New Delhi, India.
⁵ Asian Institute of Gastroenterology, Hyderabad, India.
⁶ Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
⁷ Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
⁸ Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea.
⁹ Department of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
¹⁰ Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
¹¹ Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
¹² Department of Internal Medicine, Pusan National University College of Medicine, Yangsan, Republic of Korea.
¹³ Department of Internal Medicine, Korea University College of Medicine, Seoul, Republic of Korea.
¹⁴ Department of Surgery, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
¹⁵ Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.
¹⁶ Department of Gastroenterology, Liver Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
¹⁷ Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea.
¹⁸ Center for Liver and Pancreatobiliary Cancer, National Cancer Center, Ilsan, Republic of Korea.
¹⁹ Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
²⁰ Department of Internal Medicine, Ewha Womans University, Seoul, Republic of Korea.
²¹ Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. jmyangdr@catholic.ac.kr.
²² Department of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea. kssuh@snu.ac.kr.
²³ Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
²⁴ Department of Medicine, Hospital Selayang, Batu Caves, Selangor, Malaysia.
²⁵ Sindh Institute of Urology and Transplantation, Karachi, Pakistan.
²⁶ Department of Hepatology, Alka Hospital, Lalitpur, Nepal.
²⁷ Crescent Gastroliver and General Hospital, Dhaka, Bangladesh.
²⁸ Department of Gastroenterology and Hepatology, Sir Ganga Ram Hospital New Delhi, New Delhi, India.
²⁹ TN Medical College and BYL Nair Hospital, Mumbai, India.
³⁰ University of Malaya Medical Centre, Petaling Jaya, Selangor, Malaysia.
³¹ Aster Medicity, Kochi, India.
³² Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
³³ College of Medicine, Zhejiang University, Hangzhou, China.
³⁴ Department of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
³⁵ University of Sydney, Sydney, Australia.
³⁶ Mahidol University, Nakhon Pathom, Thailand.
³⁷ Chang Gung Memorial Hospital, Taoyuan, Taiwan.
³⁸ Dr. Rela Institute, Chennai, India.
³⁹ Endoscopy Center for Diagnosis and Treatment, Taipei Veterans General Hospital, Taipei, Taiwan.
⁴⁰ Department of Gastroenterology, Yamanashi Central Hospital, Yamanashi, Japan.
⁴¹ University of Tokyo, Bunkyo City, Japan.

PMID: 38416312
DOI: 10.1007/s12072-023-10629-3

Practice Guideline

Asian Pacific Association for the Study of the Liver clinical practice guidelines on liver transplantation

Dong-Sik Kim et al. Hepatol Int. 2024 Apr.

. 2024 Apr;18(2):299-383.

doi: 10.1007/s12072-023-10629-3. Epub 2024 Feb 28.

Authors

Affiliations

¹ Department of Surgery, Korea University College of Medicine, Seoul, Republic of Korea.
² Division of Hepatobiliary Surgery and Liver Transplantation, Department of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
³ Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.
⁴ Institute of Liver and Biliary Sciences, New Delhi, India.
⁵ Asian Institute of Gastroenterology, Hyderabad, India.
⁶ Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
⁷ Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
⁸ Department of Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea.
⁹ Department of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea.
¹⁰ Department of Internal Medicine and Liver Research Institute, Seoul National University College of Medicine, Seoul, Republic of Korea.
¹¹ Department of Surgery, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
¹² Department of Internal Medicine, Pusan National University College of Medicine, Yangsan, Republic of Korea.
¹³ Department of Internal Medicine, Korea University College of Medicine, Seoul, Republic of Korea.
¹⁴ Department of Surgery, Eunpyeong St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
¹⁵ Department of Surgery, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Republic of Korea.
¹⁶ Department of Gastroenterology, Liver Center, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
¹⁷ Department of Internal Medicine, CHA Bundang Medical Center, CHA University, Seongnam, Republic of Korea.
¹⁸ Center for Liver and Pancreatobiliary Cancer, National Cancer Center, Ilsan, Republic of Korea.
¹⁹ Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.
²⁰ Department of Internal Medicine, Ewha Womans University, Seoul, Republic of Korea.
²¹ Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea. jmyangdr@catholic.ac.kr.
²² Department of Surgery, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Republic of Korea. kssuh@snu.ac.kr.
²³ Department of Hepatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh.
²⁴ Department of Medicine, Hospital Selayang, Batu Caves, Selangor, Malaysia.
²⁵ Sindh Institute of Urology and Transplantation, Karachi, Pakistan.
²⁶ Department of Hepatology, Alka Hospital, Lalitpur, Nepal.
²⁷ Crescent Gastroliver and General Hospital, Dhaka, Bangladesh.
²⁸ Department of Gastroenterology and Hepatology, Sir Ganga Ram Hospital New Delhi, New Delhi, India.
²⁹ TN Medical College and BYL Nair Hospital, Mumbai, India.
³⁰ University of Malaya Medical Centre, Petaling Jaya, Selangor, Malaysia.
³¹ Aster Medicity, Kochi, India.
³² Division of Gastroenterology and Hepatology, Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
³³ College of Medicine, Zhejiang University, Hangzhou, China.
³⁴ Department of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan.
³⁵ University of Sydney, Sydney, Australia.
³⁶ Mahidol University, Nakhon Pathom, Thailand.
³⁷ Chang Gung Memorial Hospital, Taoyuan, Taiwan.
³⁸ Dr. Rela Institute, Chennai, India.
³⁹ Endoscopy Center for Diagnosis and Treatment, Taipei Veterans General Hospital, Taipei, Taiwan.
⁴⁰ Department of Gastroenterology, Yamanashi Central Hospital, Yamanashi, Japan.
⁴¹ University of Tokyo, Bunkyo City, Japan.

PMID: 38416312
DOI: 10.1007/s12072-023-10629-3

Abstract

Liver transplantation is a highly complex and challenging field of clinical practice. Although it was originally developed in western countries, it has been further advanced in Asian countries through the use of living donor liver transplantation. This method of transplantation is the only available option in many countries in the Asia-Pacific region due to the lack of deceased organ donation. As a result of this clinical situation, there is a growing need for guidelines that are specific to the Asia-Pacific region. These guidelines provide comprehensive recommendations for evidence-based management throughout the entire process of liver transplantation, covering both deceased and living donor liver transplantation. In addition, the development of these guidelines has been a collaborative effort between medical professionals from various countries in the region. This has allowed for the inclusion of diverse perspectives and experiences, leading to a more comprehensive and effective set of guidelines.

Keywords: Deceased donor liver transplantation; Grade; Living donor liver transplantation; Multidisciplinary.

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References

1. O’Leary JG, Lepe R, Davis GL. Indications for liver transplantation. Gastroenterology. 2008;134:1764–1776 - PubMed - DOI
1. Zarrinpar A, Busuttil RW. Liver transplantation: past, present and future. Nat Rev Gastroenterol Hepatol. 2013;10:434–440 - PubMed - DOI
1. Durand F. How to improve long-term outcome after liver transplantation? Liver Int. 2018;38(Suppl 1):134–138 - PubMed - DOI
1. Chan SC, Fan ST. Historical perspective of living donor liver transplantation. World J Gastroenterol. 2008;14:15–21 - PubMed - PMC - DOI
1. Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, Schunemann HJ, GRADE Working Group. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ. 2008;336:924–926.

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[1] O’Leary JG, Lepe R, Davis GL. Indications for liver transplantation. Gastroenterology. 2008;134:1764–1776 - PubMed - DOI

[2] O’Leary JG, Lepe R, Davis GL. Indications for liver transplantation. Gastroenterology. 2008;134:1764–1776 - PubMed - DOI

[3] Zarrinpar A, Busuttil RW. Liver transplantation: past, present and future. Nat Rev Gastroenterol Hepatol. 2013;10:434–440 - PubMed - DOI

[4] Zarrinpar A, Busuttil RW. Liver transplantation: past, present and future. Nat Rev Gastroenterol Hepatol. 2013;10:434–440 - PubMed - DOI

[5] Durand F. How to improve long-term outcome after liver transplantation? Liver Int. 2018;38(Suppl 1):134–138 - PubMed - DOI

[6] Durand F. How to improve long-term outcome after liver transplantation? Liver Int. 2018;38(Suppl 1):134–138 - PubMed - DOI

[7] Chan SC, Fan ST. Historical perspective of living donor liver transplantation. World J Gastroenterol. 2008;14:15–21 - PubMed - PMC - DOI

[8] Chan SC, Fan ST. Historical perspective of living donor liver transplantation. World J Gastroenterol. 2008;14:15–21 - PubMed - PMC - DOI

[9] Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, Schunemann HJ, GRADE Working Group. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ. 2008;336:924–926.

[10] Guyatt GH, Oxman AD, Vist GE, Kunz R, Falck-Ytter Y, Alonso-Coello P, Schunemann HJ, GRADE Working Group. GRADE: an emerging consensus on rating quality of evidence and strength of recommendations. BMJ. 2008;336:924–926.

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Asian Pacific Association for the Study of the Liver clinical practice guidelines on liver transplantation

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Asian Pacific Association for the Study of the Liver clinical practice guidelines on liver transplantation

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