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. 2024 Jun;28(6):979-983.
doi: 10.1007/s10995-024-03917-3. Epub 2024 Feb 28.

Birth Outcomes Among People with Hepatitis C in Pregnancy - Three U.S. States, 2018-2021

Kate R Woodworth  1 , Suzanne M Newton  2 , Ayzsa Tannis  3 , Megan R Reynolds  2 , Emily O Olsen  2 , Lindsey Sizemore  4 , Heather Wingate  4 , Lauren Orkis  5 , Bethany Reynolds  5 , Nicole Longcore  6 , Nadia Thomas  6 , Shin Y Kim  2 , Lakshmi Panagiotakopoulos  7 , Carolyn Wester  7 , Dana Meaney Delman  2 , Suzanne M Gilboa  2 , Van T Tong  2
Affiliations

Birth Outcomes Among People with Hepatitis C in Pregnancy - Three U.S. States, 2018-2021

Kate R Woodworth et al. Matern Child Health J. 2024 Jun.

Abstract

Introduction: There are limited and conflicting data regarding the impact of hepatitis C in pregnancy on adverse birth outcomes.

Methods: Using the Surveillance for Emerging Threats to Pregnant People and Infants Network (SET-NET), a large surveillance cohort, we describe birth outcomes among a cohort of people with HCV in pregnancy in total and by reported substance use.

Results: Among 1418 infants, 89% were born to people with reported substance use during pregnancy. The proportion born preterm was 20%, 13% were small-for-gestational age and 34% of term infants required intensive care.

Conclusions: Assessments of recent changes to recommendations for HCV screening in pregnancy should evaluate the impact on maternal access to care for both HCV treatment as well as comorbidities such as substance use disorder which may contribute to adverse birth outcomes.

Keywords: Adverse pregnancy outcomes; Hepatitis C; Preterm birth; Substance use.

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Conflict of interest statement

Conflict of Interest The authors report no conflicts of interest.

References

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